SEELEY'S ESS OF ANATOMY & PHYSIOLOGY
11th Edition
ISBN: 9781264802463
Author: VanPutte
Publisher: MCG CUSTOM
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Chapter 13.3, Problem 7AYP
How are the gray matter and white matter arranged in the cerebellum? What is the arbor vitae?
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1. In vivo testing provides valuable insight into a drug’s kinetics. Assessing drug kinetics following multiple different routes of administration provides greater insight than just a single route of administration alone. The following data was collected in 250 g rats following bolus iv, oral (po), and intraperitoneal (ip) administration.Using this data and set of graphs, determine:
(a) k, C0, V, and AUC* for the bolus iv data (b) k, ka, B1, and AUC* for the po data (c) k, ka, B1, and AUC* for the ip data (d) relative bioavailability for po vs ip, Fpo/Fip (e) absolute po bioavailability, (f)Fpo absolute ip bioavailability, Fip
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2. Drug quantification from plasma is commonly performed by using techniques such as HPLC or LC/MS. However, these methods do have limitations, and investigators may choose to use a radiolabeled analog of a drug instead. Radioligands are molecules that contain radioactive isotopes, commonly 3H or 14C. This technique allows investigators to quantify drug concentration from radiation measurements. The following measurements were made in 250 g rats following oral administration of 18.2 µCi of a 14C-labeled drug of interest: Time (min) Plasma Radiation Levels (µCi/L) 0 0.0 2 9.7 4 19.2 7 25.3 9 37.8 12 39.6 14 45.8 17 48.8 20 52.0 25 56.4 30 59.2 35 60.1 40 61.1 45 62.1 50 62.8 60 63.1 70 62.1 80 60.1 90 57.3 100 55.5 110 53.7 120 52.2 150 48.0 180 45.0 240 39.0
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The current nutrition labelling regulation in Hong Kong requires food manufacturer to list E+7 information on the package of pre-packaged food products. Do you think that more nutrients, such as calcium and cholesterol, shall be included?
Chapter 13 Solutions
SEELEY'S ESS OF ANATOMY & PHYSIOLOGY
Ch. 13.1 - Name the five pouches of the neural tube and the...Ch. 13.1 - What do the cavities of the neural tube become in...Ch. 13.2 - Prob. 3AYPCh. 13.2 - Prob. 4AYPCh. 13.2 - Prob. 5AYPCh. 13.2 - Prob. 6AYPCh. 13.3 - How are the gray matter and white matter arranged...Ch. 13.3 - Whet are the major regions of the cerebellum? What...Ch. 13.4 - Prob. 9AYPCh. 13.4 - Prob. 10AYP
Ch. 13.4 - Prob. 11AYPCh. 13.4 - List and explain the of the hypothalamus.Ch. 13.5 - Distinguish between gyri and sulci. What...Ch. 13.5 - Prob. 14AYPCh. 13.5 - Prob. 15AYPCh. 13.5 - Prob. 16AYPCh. 13.5 - List the basal nuclei, and state their general...Ch. 13.5 - Prob. 18AYPCh. 13.6 - Prob. 19AYPCh. 13.6 - Describe the contents of the dural sinuses,...Ch. 13.6 - Prob. 21AYPCh. 13.6 - Prob. 22AYPCh. 13.7 - Prob. 23AYPCh. 13.7 - Prob. 24AYPCh. 13.8 - Prob. 25AYPCh. 13.8 - Prob. 26AYPCh. 13.8 - Prob. 27AYPCh. 13.8 - Prob. 28AYPCh. 13.8 - Prob. 29AYPCh. 13.8 - Prob. 30AYPCh. 13.8 - Prob. 31AYPCh. 13 - Which of these parts of the embryonic brain is...Ch. 13 - To separate the brainstem from the rest of the...Ch. 13 - Prob. 3RACCh. 13 - Prob. 4RACCh. 13 - Prob. 5RACCh. 13 - Prob. 6RACCh. 13 - Prob. 7RACCh. 13 - Prob. 8RACCh. 13 - Prob. 9RACCh. 13 - Prob. 10RACCh. 13 - Prob. 11RACCh. 13 - Prob. 12RACCh. 13 - Prob. 13RACCh. 13 - Prob. 14RACCh. 13 - The basal nuclei are located in the a. inferior...Ch. 13 - Prob. 16RACCh. 13 - Prob. 17RACCh. 13 - Prob. 18RACCh. 13 - Water-soluble molecules of the blood plasma move...Ch. 13 - Prob. 20RACCh. 13 - The cranial nerve responsible for facusing the eye...Ch. 13 - Prob. 22RACCh. 13 - Prob. 23RACCh. 13 - Prob. 24RACCh. 13 - Prob. 25RACCh. 13 - Prob. 26RACCh. 13 - Prob. 1CTCh. 13 - Prob. 2CTCh. 13 - Prob. 3CTCh. 13 - Describe a clinical test to evaluate each of the...Ch. 13 - Prob. 5CTCh. 13 - Prob. 6CTCh. 13 - Following a car accident in which he hit the left...Ch. 13 - Over the past month, Andy has noticed that...Ch. 13 - Prob. 9CT
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