Chapter 13.11, Problem 20CC

(a)

Interpretation Introduction

Interpretation: The reagents used in preparation of following Thiols are to be given.

Concept Introduction:

The replacement of $\text{OH}$ groups with $\text{SH}$ is called Thiols. The preparation of Thiols takes place by ${\text{S}}_{\text{N}}\text{2}$   reaction of Sodium hydroxide with suitable Alkyl halide.

This reaction even occurs when secondary substrate without opposing $\text{E2}$ reactions, because the hydrosulphide ion is an excellent substrate and poor base. The attack of nucleophile at chirality centre, results in inversion of configuration.

(b)

Interpretation Introduction

Interpretation: The reagents used in preparation of following Thiols are to be given.

Concept Introduction:

The replacement of $\text{OH}$ groups with $\text{SH}$  is called Thiols. The preparation of Thiols takes place by ${\text{S}}_{\text{N}}\text{2}$  reaction of Sodium hydroxide with suitable Alkyl halide.

This reaction even occurs when secondary substrate without opposing $\text{E2}$ reactions, because the hydrosulphide ion is an excellent substrate and poor base. The attack of nucleophile at chirality centre, results in inversion of configuration.

(c)

Interpretation Introduction

Interpretation: The reagents used in preparation of following Thiols are to be given.

Concept Introduction:

The replacement of $\text{OH}$ groups with $\text{SH}$  is called Thiols. The preparation of Thiols takes place by ${\text{S}}_{\text{N}}\text{2}$  reaction of Sodium hydroxide with suitable Alkyl halide.

This reaction even occurs when secondary substrate without opposing $\text{E2}$ reactions, because the hydrosulphide ion is an excellent substrate and poor base. The attack of nucleophile at chirality centre, results in inversion of configuration.