Concept explainers
To describe:
Hepatitis B infections caused by a needlestick during a dental procedure by using the terms given in question, also determine the mode of transmission of the following disease.
Introduction:
Hepatitis B is a disease of liver which is caused by infection of virus. The virus responsible for hepatitis B is HBV (hepatitis B virus) and it belongs to Hepadnaviridae family of viruses.
To describe:
Pneumocystis pneumonia in an AIDS patient and also determine the mode of transmission of the following disease.
Introduction:
HIV is human immunodeficiency virus which causes a very serious disease called AIDS (acquired immunodeficiency syndrome). HIV interferes with the immune cells of the body and reduces the ability to fight infections.
To describe:
Bubonic plague that is acquired through the bite of a rat flea, and also determine the mode of transmission.
Introduction:
Bubonic plague is a type of bacterial infection caused by bacterium Yersinia pestis. This plague may have deadly effects. It can be spread from the bite of an infected rodent or flea. The plague is characterized by symptoms like fever, headache, swollen and painful lesions, and vomiting.
To determine:
Hantavirus pulmonary syndrome infection acquired while vacationing in a log cabin.
Introduction:
Hantavirus pulmonary syndrome is a viral infection which develops its symptoms within a week. It is a fatal, respiratory disease that occurs in human by infection caused by hantaviruses.
To describe:
The disease salmonellosis and also determine the mode of transmission.
Introduction:
Salmonellosis is a type of bacterial infection caused by the strain of Salmonella bacterium. This bacterium mainly transmitted to humans through contaminated food or water. The infection results in typhoid fever and sometimes it causes severe deadly disease.
To describe:
The undiagnosed chlamydiosis and also determine the mode of transmission of the disease.
Introduction:
Chlamydiosis is a common sexually transmitted disease. It is caused by the bacteria called Chlamydia trachomatis. It can infect both men and women. Chlamydia doesn’t usually cause any symptoms.
To describe:
The disease mononucleosis that is transmitted via a shared drinking glass.
Introduction:
Respiratory droplet and saliva is the exit route for several viruses, including those of mumps, rabies, and infectious mononucleosis. Mononucleosis includes a viral disease caused by Epstein-Barr virus.
To describe:
The disease neonatal gonorrhea and also determine the mode of transmission of this disease.
Introduction:
Gonorrhea is a sexually transmitted disease which causes infection in the reproductive part of females. This infection can also pass to the newborns known as neonatal gonorrhea.
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Microbiology: A Systems Approach
- P You are studying a population of 100 flowers that has two alleles at a locus for flower color, blue (B) and green (G). There are 15 individuals with the BB genotype, 70 individuals with the BG genotype, and 15 individuals with the GG genotype. (a) What are the allele frequencies of B and G in the starting population? Show your calculations. (2 pts) (b) Is this population in Hardy-Weinberg equilibrium? Show your calculations. (3 pts) 12pt v Paragraph BIU UA AV & VT2V f CO Varrow_forwardIn a natural population of outbreeding plants, the variance of the total number of seeds per plant is 16. From the natural population, 20 plants are taken into the laboratory and developed into separate true-breeding lines by self- fertilization-with selection for high, low, or medium number of seeds-for 10 generations. The average variance in the tenth generation in each of the 20 sets is about equal and averages 5.8 across all the sets. Estimate the broad-sense heritability for seed number in this population. (4 pts) 12pt v Paragraph BIUA V V T² v B ① O wordsarrow_forwardIn a natural population of outbreeding plants, the variance of the total number of seeds per plant is 16. From the natural population, 20 plants are taken into the laboratory and developed into separate true-breeding lines by self- fertilization-with selection for high, low, or medium number of seeds-for 10 generations. The average variance in the tenth generation in each of the 20 sets is about equal and averages 5.8 across all the sets. Estimate the broad-sense heritability for seed number in this population. (4 pts) 12pt v Paragraph BI DI T² v ✓ B°arrow_forward
- Question 1 In a population of Jackalopes (pictured below), horn length will vary between 0.5 and 2 feet, with the mean length somewhere around 1.05 feet. You pick Jackalopes that have horn lengths around 1.75 feet to breed as this appears to be the optimal length for battling other Jackalopes for food. After a round of breeding, you measure the offsprings' mean horn length is 1.67. What is the heritability of horns length (h2)? Is Jackalope horn length a heritable trait? (4 pts)? 12pt v Paragraph BIU A ✓arrow_forwardFrequency of allele A1 Question 2 The graph below shows results of two simulations, both depicting the rise in frequency of beneficial allele in a population of infinite size. The selection coefficient and the starting frequency are the same, but in one simulation the beneficial allele is dominant and in the other it is recessive. Neither allele is fixed by 500 generations. 1.0 1 0.8 0.6 0.4 2 0.2 0 0 100 200 300 400 500 Generation (a) Which simulation shows results for a dominant and which shows results for a recessive allele? How can you tell? (4 pts) (b) Neither of the alleles reaches fixation by 500 generations. If given enough time, will both of these alleles reach fixation in the population? Why or why not? (3 pts) 12pt Paragraph BIU AT2v Varrow_forwardQuestion 14 The relative fitnesses of three genotypes are WA/A= 1.0, WA/a = 0.7, and Wa/a = 0.3. If the population starts at the allele frequency p = 0.5, what is the value of p in the next generation? (3 pts) 12pt v V Paragraph B I U D V T² v V V p O words <arrow_forward
- According to a recent study, 1 out of 50,000 people will be diagnosed with cystic fibrosis. Cystic fibrosis can be caused by a mutant form of the CFTR gene (dominant gene symbol is F and mutant is f). A. Using the rate of incidence above, what is the frequency of carriers of the cystic fibrosis allele for CFTR in the US? (3 pts) B. In a clinical study, 400 people from the population mentioned in (A.) were genotyped for BRCA1 Listed below are the results. Are these results in Hardy- Weinberg equilibrium? Use Chi Square to show whether or not they are. (3 pts) BRCA1 genotype # of women 390 BB Bb bb 10 0 12pt Paragraph L BIUAV V T² v Varrow_forwardOutline a method for using apomixis to maintain feminized CannabisAssume apomixis is controlled by a single dominant gene. You can choose the type of apomixis: obligate or facultative, gametophytic or sporophytic. Discuss advantages and disadvantages of your proposed method.arrow_forwardKinetics: One-Compartment First-Order Absorption 1. In vivo testing provides valuable insight into a drug’s kinetics. Assessing drug kinetics following multiple routes of administration provides greater insight than a single route of administration alone. The following data was collected in 250-g rats following bolus IV, oral (PO), and intraperitoneal (ip) administration. Using this data and set of graphs, determine:(calculate for each variable) (a) k, C0, V, and AUC* for the bolus iv data (b) k, ka, B1, and AUC* for the po data c) k, ka, B1, and AUC* for the ip data (d) relative bioavailability for po vs ip, Fpo/Fip (e)absolute ip bioavailability, Fip (f) absolute po bioavailability, Fpoarrow_forward
- 3. A promising new drug is being evaluated in human trials. Based on preliminary human tests, this drug is most effective when plasma levels exceed 30 mg/L. Measurements from preliminary tests indicate the following human pharmacokinetic parameter values: t1/2,elim = 4.6hr, t1/2,abs = 0.34hr, VD = 0.29 L/kg, Foral = 72%. Based on these parameters, estimate the following if a 49 kg woman were to receive a 1000mg oral dose of this drug: (a) Estimate the plasma concentration of the drug at 1hr, 6 hr, and 20hr after taking the drug ( Concentration estimate) (b) Estimate the time for maximum plasma concentration (tmax). (c) Estimate the maximum plasma concentration (Cmax). (d) Estimate the time at which the plasma level first rises above 30 mg/L. (Note this is a trial and error problem where you must guess a time, plug it into the concentration equation, and determine if it is close to 30 mg/L. Hint: based on part (a) it should be apparent that the answer is less than 1hr.) (e)…arrow_forwardList substitutions in your diet you could make to improve it based on what you know now about a balanced diet. For instance, if you like to drink soda, you might substitute skim milk or water for some of the soft drinks you consumed. List the item you wish to replace with the new item and what you hope to accomplish with that substitution. Be sure to choose foods you know that you'd enjoy and you consider more "healthful." If you feel your diet is already balanced, describe how you accomplish your balanced intake and when you began eating this way.arrow_forwardWhich single food item contained you ate for the 3 days with the most sodium?arrow_forward
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