1 SEM ACC W/RAVEN CARDED
1 SEM ACC W/RAVEN CARDED
12th Edition
ISBN: 9781265486297
Author: Raven
Publisher: MCGRAW-HILL HIGHER EDUCATION
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Chapter 13, Problem 6A
Summary Introduction

The biological event taking place in a cell undergoing meiotic division in which a pair of homologous chromosomes or the sister chromatids fail to separate is called non-disjunction.

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22. Which of the following mutant proteins is expected to have a dominant negative effect when over-   expressed in normal cells?   a. mutant PI3-kinase that lacks the SH2 domain but retains the kinase function   b. mutant Grb2 protein that cannot bind to RTK   c. mutant RTK that lacks the extracellular domain   d. mutant PDK that has the PH domain but lost the kinase function   e. all of the above
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