Concepts of Genetics (12th Edition)
Concepts of Genetics (12th Edition)
12th Edition
ISBN: 9780134604718
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
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Chapter 13, Problem 30ESP

The genetic code is degenerate. Amino acids are encoded by either 1, 2, 3,4, or 6 triplet codons (see Figure 13.7). An interesting question is whether the number of triplet codes for a given amino acid is in any way correlated with the frequency with which that amino acid appears in proteins. That is, is the genetic code optimized for its intended use? Some approximations of the frequency of appearance of nine amino acids in proteins in E. coli are given in the following:

Chapter 13, Problem 30ESP, The genetic code is degenerate. Amino acids are encoded by either 1, 2, 3,4, or 6 triplet codons

  1. (a) Determine how many triplets encode each amino acid.
  2. (b) Devise a way to graphically compare the two sets of information (data).
  3. (c) Analyze your data to determine what, if any, correlations can be drawn between the relative frequency of amino acids making up proteins and the number of codons for each. Write a paragraph that states your specific and general conclusions.
  4. (d) How would you proceed with your analysis if you wanted to pursue this problem further?
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We will be starting a group project next week where you and your group will research and ultimately present on a current research article related to the biology of a pathogen that infects humans. The article could be about the pathogen itself, the disease process related to the pathogen, the immune response to the pathogen, vaccines or treatments that affect the pathogen, or other biology-related study about the pathogen. I recommend that you choose a pathogen that is currently interesting to researchers, so that you will be able to find plenty of articles about it. Avoid choosing a historical disease that no longer circulates. List 3 possible pathogens or diseases that you might want to do for your group project.
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Concepts of Genetics (12th Edition)

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