Blinding What does it mean when we say that the study cited in Exercise 1 was “double-blind”?
1. Back Pain Treatment In a study designed to test the effectiveness of paracetamol (or acetaminophen) as a treatment for lower back pain, 1643 patients were randomly assigned to one of three groups: (1) the 547 subjects in the placebo group were given pills containing no medication; (2) 350 subjects were in a group given pills with paracetamol taken at regular intervals; (3) 546 subjects were in a group given pills with paracetamol to be taken when needed for pain relief. (See “Efficacy of Paracetamol for Acute Low-Back Pain,” by Williams, et al., Lancet, doi: 10.1016/S0140-6736(14)60805-9.) Is this study an experiment or an observational study? Explain.
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Chapter 1 Solutions
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