BIOCHEMISTRY (LOOSELEAF)-W/ACCESS
BIOCHEMISTRY (LOOSELEAF)-W/ACCESS
9th Edition
ISBN: 9781319425784
Author: BERG
Publisher: Macmillan Higher Education
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Chapter 13, Problem 28P
Interpretation Introduction

(a)

Interpretation:

The most sensitive member of the ASIC family to toxin needs to be determined.

Concept introduction:

The acid sensing ion channels which are commonly known as ASIC are the proton sensing channels present in the central nervous system which are reactive towards a variety of complex behaviors such as fear, anxiety, pain, depression, leaning and sensitivity.ASIC1a, ASIC1b, ASIC2a, ASIC2b, ASIC3, and ASIC4 are six different subunits of such acid sensing ion channels.

Interpretation Introduction

(b)

Interpretation:

Whether the effect of the toxin is reversible or irreversible needs to be explained.

Concept introduction:

The acid sensing ion channels which are commonly known as ASIC are the proton sensing channels present in the central nervous system which are reactive towards a variety of complex behaviors such as fear, anxiety, pain, depression, leaning and sensitivity.

Interpretation Introduction

(c)

Interpretation:

The percentage of PcTx1 that yields 50% inhibition of the sensitive channel needs to be determined.

Concept introduction:

The acid sensing ion channels which are commonly known as ASIC are the proton sensing channels present in central nervous system which are reactive towards a variety of complex behaviors such as fear, anxiety, pain, depression, leaning and sensitivity.

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