(a) Interpretation: The most sensitive member of the ASIC family to toxin needs to be determined. Concept introduction: The acid sensing ion channels which are commonly known as ASIC are the proton sensing channels present in the central nervous system which are reactive towards a variety of complex behaviors such as fear, anxiety, pain, depression, leaning and sensitivity.ASIC1a, ASIC1b, ASIC2a, ASIC2b, ASIC3, and ASIC4 are six different subunits of such acid sensing ion channels.

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Answer 1

Question

Chapter 13, Problem 28P

Interpretation Introduction

(a)

Interpretation:

The most sensitive member of the ASIC family to toxin needs to be determined.

Concept introduction:

The acid sensing ion channels which are commonly known as ASIC are the proton sensing channels present in the central nervous system which are reactive towards a variety of complex behaviors such as fear, anxiety, pain, depression, leaning and sensitivity.ASIC1a, ASIC1b, ASIC2a, ASIC2b, ASIC3, and ASIC4 are six different subunits of such acid sensing ion channels.

Interpretation Introduction

(b)

Interpretation:

Whether the effect of the toxin is reversible or irreversible needs to be explained.

Concept introduction:

The acid sensing ion channels which are commonly known as ASIC are the proton sensing channels present in the central nervous system which are reactive towards a variety of complex behaviors such as fear, anxiety, pain, depression, leaning and sensitivity.

Interpretation Introduction

(c)

Interpretation:

The percentage of PcTx1 that yields 50% inhibition of the sensitive channel needs to be determined.

Concept introduction:

The acid sensing ion channels which are commonly known as ASIC are the proton sensing channels present in central nervous system which are reactive towards a variety of complex behaviors such as fear, anxiety, pain, depression, leaning and sensitivity.

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Answer 2

Question

Chapter 13, Problem 28P

Interpretation Introduction

(a)

Interpretation:

The most sensitive member of the ASIC family to toxin needs to be determined.

Concept introduction:

The acid sensing ion channels which are commonly known as ASIC are the proton sensing channels present in the central nervous system which are reactive towards a variety of complex behaviors such as fear, anxiety, pain, depression, leaning and sensitivity.ASIC1a, ASIC1b, ASIC2a, ASIC2b, ASIC3, and ASIC4 are six different subunits of such acid sensing ion channels.

Interpretation Introduction

(b)

Interpretation:

Whether the effect of the toxin is reversible or irreversible needs to be explained.

Concept introduction:

The acid sensing ion channels which are commonly known as ASIC are the proton sensing channels present in the central nervous system which are reactive towards a variety of complex behaviors such as fear, anxiety, pain, depression, leaning and sensitivity.

Interpretation Introduction

(c)

Interpretation:

The percentage of PcTx1 that yields 50% inhibition of the sensitive channel needs to be determined.

Concept introduction:

The acid sensing ion channels which are commonly known as ASIC are the proton sensing channels present in central nervous system which are reactive towards a variety of complex behaviors such as fear, anxiety, pain, depression, leaning and sensitivity.

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Answer 3

Question

Chapter 13, Problem 28P

Interpretation Introduction

(a)

Interpretation:

The most sensitive member of the ASIC family to toxin needs to be determined.

Concept introduction:

The acid sensing ion channels which are commonly known as ASIC are the proton sensing channels present in the central nervous system which are reactive towards a variety of complex behaviors such as fear, anxiety, pain, depression, leaning and sensitivity.ASIC1a, ASIC1b, ASIC2a, ASIC2b, ASIC3, and ASIC4 are six different subunits of such acid sensing ion channels.

Interpretation Introduction

(b)

Interpretation:

Whether the effect of the toxin is reversible or irreversible needs to be explained.

Concept introduction:

The acid sensing ion channels which are commonly known as ASIC are the proton sensing channels present in the central nervous system which are reactive towards a variety of complex behaviors such as fear, anxiety, pain, depression, leaning and sensitivity.

Interpretation Introduction

(c)

Interpretation:

The percentage of PcTx1 that yields 50% inhibition of the sensitive channel needs to be determined.

Concept introduction:

The acid sensing ion channels which are commonly known as ASIC are the proton sensing channels present in central nervous system which are reactive towards a variety of complex behaviors such as fear, anxiety, pain, depression, leaning and sensitivity.

Expert Solution & Answer

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Answer 4

Question

Chapter 13, Problem 28P

Interpretation Introduction

(a)

Interpretation:

The most sensitive member of the ASIC family to toxin needs to be determined.

Concept introduction:

The acid sensing ion channels which are commonly known as ASIC are the proton sensing channels present in the central nervous system which are reactive towards a variety of complex behaviors such as fear, anxiety, pain, depression, leaning and sensitivity.ASIC1a, ASIC1b, ASIC2a, ASIC2b, ASIC3, and ASIC4 are six different subunits of such acid sensing ion channels.

Interpretation Introduction

(b)

Interpretation:

Whether the effect of the toxin is reversible or irreversible needs to be explained.

Concept introduction:

The acid sensing ion channels which are commonly known as ASIC are the proton sensing channels present in the central nervous system which are reactive towards a variety of complex behaviors such as fear, anxiety, pain, depression, leaning and sensitivity.

Interpretation Introduction

(c)

Interpretation:

The percentage of PcTx1 that yields 50% inhibition of the sensitive channel needs to be determined.

Concept introduction:

The acid sensing ion channels which are commonly known as ASIC are the proton sensing channels present in central nervous system which are reactive towards a variety of complex behaviors such as fear, anxiety, pain, depression, leaning and sensitivity.

Expert Solution & Answer

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Answer 5

Chapter 13, Problem 28P

Interpretation Introduction

(a)

Interpretation:

The most sensitive member of the ASIC family to toxin needs to be determined.

Concept introduction:

The acid sensing ion channels which are commonly known as ASIC are the proton sensing channels present in the central nervous system which are reactive towards a variety of complex behaviors such as fear, anxiety, pain, depression, leaning and sensitivity.ASIC1a, ASIC1b, ASIC2a, ASIC2b, ASIC3, and ASIC4 are six different subunits of such acid sensing ion channels.

Interpretation Introduction

(b)

Interpretation:

Whether the effect of the toxin is reversible or irreversible needs to be explained.

Concept introduction:

The acid sensing ion channels which are commonly known as ASIC are the proton sensing channels present in the central nervous system which are reactive towards a variety of complex behaviors such as fear, anxiety, pain, depression, leaning and sensitivity.

Interpretation Introduction

(c)

Interpretation:

The percentage of PcTx1 that yields 50% inhibition of the sensitive channel needs to be determined.

Concept introduction:

The acid sensing ion channels which are commonly known as ASIC are the proton sensing channels present in central nervous system which are reactive towards a variety of complex behaviors such as fear, anxiety, pain, depression, leaning and sensitivity.

Answer 6

Chapter 13, Problem 28P

Interpretation Introduction

(a)

Interpretation:

The most sensitive member of the ASIC family to toxin needs to be determined.

Concept introduction:

The acid sensing ion channels which are commonly known as ASIC are the proton sensing channels present in the central nervous system which are reactive towards a variety of complex behaviors such as fear, anxiety, pain, depression, leaning and sensitivity.ASIC1a, ASIC1b, ASIC2a, ASIC2b, ASIC3, and ASIC4 are six different subunits of such acid sensing ion channels.

Answer 7

Chapter 13, Problem 28P

Interpretation Introduction

(a)

Interpretation:

The most sensitive member of the ASIC family to toxin needs to be determined.

Concept introduction:

The acid sensing ion channels which are commonly known as ASIC are the proton sensing channels present in the central nervous system which are reactive towards a variety of complex behaviors such as fear, anxiety, pain, depression, leaning and sensitivity.ASIC1a, ASIC1b, ASIC2a, ASIC2b, ASIC3, and ASIC4 are six different subunits of such acid sensing ion channels.

Answer 8

Interpretation Introduction

(b)

Interpretation:

Whether the effect of the toxin is reversible or irreversible needs to be explained.

Concept introduction:

The acid sensing ion channels which are commonly known as ASIC are the proton sensing channels present in the central nervous system which are reactive towards a variety of complex behaviors such as fear, anxiety, pain, depression, leaning and sensitivity.

Answer 9

Interpretation Introduction

(b)

Interpretation:

Whether the effect of the toxin is reversible or irreversible needs to be explained.

Concept introduction:

The acid sensing ion channels which are commonly known as ASIC are the proton sensing channels present in the central nervous system which are reactive towards a variety of complex behaviors such as fear, anxiety, pain, depression, leaning and sensitivity.

Answer 10

Interpretation Introduction

(c)

Interpretation:

The percentage of PcTx1 that yields 50% inhibition of the sensitive channel needs to be determined.

Concept introduction:

The acid sensing ion channels which are commonly known as ASIC are the proton sensing channels present in central nervous system which are reactive towards a variety of complex behaviors such as fear, anxiety, pain, depression, leaning and sensitivity.

Answer 11

Interpretation Introduction

(c)

Interpretation:

The percentage of PcTx1 that yields 50% inhibition of the sensitive channel needs to be determined.

Concept introduction:

The acid sensing ion channels which are commonly known as ASIC are the proton sensing channels present in central nervous system which are reactive towards a variety of complex behaviors such as fear, anxiety, pain, depression, leaning and sensitivity.

Answer 12

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Answer 13

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Answer 14

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Answer 15

Ch. 13 - Prob. 1P Ch. 13 - Prob. 2P Ch. 13 - Prob. 3P Ch. 13 - Prob. 4P Ch. 13 - Prob. 5P Ch. 13 - Prob. 6P Ch. 13 - Prob. 7P Ch. 13 - Prob. 8P Ch. 13 - Prob. 9P Ch. 13 - Prob. 10P

Solution Summary: The author explains that the most sensitive member of the ASIC family to toxin needs to be determined.

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