Concept explainers
(a)
Interpretation:
The factor by which an open to closed ratio increases by the binding of the firstacetylcholine molecule and the second acetylcholine molecule needs to be explained.
Concept introduction:
Acetylcholine act as a neurotransmitter which means, it sends messages or chemicals from one cell to another cell of the body. Acetylcholinesterase helps in stopping the excitation of a nerve cell after the transmission of impulse. In other words, this enzyme causes rapid hydrolysis of acetylcholine.
(b)
Interpretation:
The corresponding free energy contribution of the channel at
Concept introduction:
Acetylcholine act as a neurotransmitter which means it sends messages or chemicals from one cell to another cell of the body. Acetylcholinesterase helps in stopping the excitation of a nerve cell after the transmission of impulse or in other words, we can say that this enzyme causes rapid hydrolysis of acetylcholine.
(c)
Interpretation:
Whether the allosteric transition be accounted for the MWC concerted mode or not needs to be explained.
Concept introduction:
Acetylcholine acts as a neurotransmitter which means, it sends messages or chemicals from one cell to another cell of the body. Acetylcholinesterase helps in stopping the excitation of a nerve cell after the transmission of impulse or in other words, one can say that this enzyme causes rapid hydrolysis of acetylcholine.

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Chapter 13 Solutions
BIOCHEMISTRY
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