(a) Interpretation: The factor by which an open to closed ratio increases by the binding of the firstacetylcholine molecule and the second acetylcholine molecule needs to be explained. Concept introduction: Acetylcholine act as a neurotransmitter which means, it sends messages or chemicals from one cell to another cell of the body. Acetylcholinesterase helps in stopping the excitation of a nerve cell after the transmission of impulse. In other words, this enzyme causes rapid hydrolysis of acetylcholine.

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Answer 1

Question

Chapter 13, Problem 22P

Interpretation Introduction

(a)

Interpretation:

The factor by which an open to closed ratio increases by the binding of the firstacetylcholine molecule and the second acetylcholine molecule needs to be explained.

Concept introduction:

Acetylcholine act as a neurotransmitter which means, it sends messages or chemicals from one cell to another cell of the body. Acetylcholinesterase helps in stopping the excitation of a nerve cell after the transmission of impulse. In other words, this enzyme causes rapid hydrolysis of acetylcholine.

Interpretation Introduction

(b)

Interpretation:

The corresponding free energy contribution of the channel at 250C needs to be determined.

Concept introduction:

Acetylcholine act as a neurotransmitter which means it sends messages or chemicals from one cell to another cell of the body. Acetylcholinesterase helps in stopping the excitation of a nerve cell after the transmission of impulse or in other words, we can say that this enzyme causes rapid hydrolysis of acetylcholine.

Interpretation Introduction

(c)

Interpretation:

Whether the allosteric transition be accounted for the MWC concerted mode or not needs to be explained.

Concept introduction:

Acetylcholine acts as a neurotransmitter which means, it sends messages or chemicals from one cell to another cell of the body. Acetylcholinesterase helps in stopping the excitation of a nerve cell after the transmission of impulse or in other words, one can say that this enzyme causes rapid hydrolysis of acetylcholine.

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Macmillan Learning Cholesterol synthesis begins with the formation of mevalonate from acetyl CoA. This process activates mevalonate and converts it to isopentenyl pyrophosphate. Identify the atoms in mevalonate and isopentenyl pyrophosphate that will be labeled from acetyl CoA labeled with 14C in the carbonyl carbon. Place 14C atoms and C atoms to denote which carbon atoms are labeled and which are not labeled. H₂C COA 14C-labeled acetyl-CoA HHH [c] H H OH 014C - OH H HH H Mevalonate CH3 H H 14C H Η H H Incorrect Answer of o -P-O-P-0- Isopentenyl pyrophosphate с Answer Bank 14C

Answer 2

Question

Chapter 13, Problem 22P

Interpretation Introduction

(a)

Interpretation:

The factor by which an open to closed ratio increases by the binding of the firstacetylcholine molecule and the second acetylcholine molecule needs to be explained.

Concept introduction:

Acetylcholine act as a neurotransmitter which means, it sends messages or chemicals from one cell to another cell of the body. Acetylcholinesterase helps in stopping the excitation of a nerve cell after the transmission of impulse. In other words, this enzyme causes rapid hydrolysis of acetylcholine.

Interpretation Introduction

(b)

Interpretation:

The corresponding free energy contribution of the channel at 250C needs to be determined.

Concept introduction:

Acetylcholine act as a neurotransmitter which means it sends messages or chemicals from one cell to another cell of the body. Acetylcholinesterase helps in stopping the excitation of a nerve cell after the transmission of impulse or in other words, we can say that this enzyme causes rapid hydrolysis of acetylcholine.

Interpretation Introduction

(c)

Interpretation:

Whether the allosteric transition be accounted for the MWC concerted mode or not needs to be explained.

Concept introduction:

Acetylcholine acts as a neurotransmitter which means, it sends messages or chemicals from one cell to another cell of the body. Acetylcholinesterase helps in stopping the excitation of a nerve cell after the transmission of impulse or in other words, one can say that this enzyme causes rapid hydrolysis of acetylcholine.

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Answer 3

Question

Chapter 13, Problem 22P

Interpretation Introduction

(a)

Interpretation:

The factor by which an open to closed ratio increases by the binding of the firstacetylcholine molecule and the second acetylcholine molecule needs to be explained.

Concept introduction:

Acetylcholine act as a neurotransmitter which means, it sends messages or chemicals from one cell to another cell of the body. Acetylcholinesterase helps in stopping the excitation of a nerve cell after the transmission of impulse. In other words, this enzyme causes rapid hydrolysis of acetylcholine.

Interpretation Introduction

(b)

Interpretation:

The corresponding free energy contribution of the channel at 250C needs to be determined.

Concept introduction:

Acetylcholine act as a neurotransmitter which means it sends messages or chemicals from one cell to another cell of the body. Acetylcholinesterase helps in stopping the excitation of a nerve cell after the transmission of impulse or in other words, we can say that this enzyme causes rapid hydrolysis of acetylcholine.

Interpretation Introduction

(c)

Interpretation:

Whether the allosteric transition be accounted for the MWC concerted mode or not needs to be explained.

Concept introduction:

Acetylcholine acts as a neurotransmitter which means, it sends messages or chemicals from one cell to another cell of the body. Acetylcholinesterase helps in stopping the excitation of a nerve cell after the transmission of impulse or in other words, one can say that this enzyme causes rapid hydrolysis of acetylcholine.

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Answer 4

Question

Chapter 13, Problem 22P

Interpretation Introduction

(a)

Interpretation:

The factor by which an open to closed ratio increases by the binding of the firstacetylcholine molecule and the second acetylcholine molecule needs to be explained.

Concept introduction:

Acetylcholine act as a neurotransmitter which means, it sends messages or chemicals from one cell to another cell of the body. Acetylcholinesterase helps in stopping the excitation of a nerve cell after the transmission of impulse. In other words, this enzyme causes rapid hydrolysis of acetylcholine.

Interpretation Introduction

(b)

Interpretation:

The corresponding free energy contribution of the channel at 250C needs to be determined.

Concept introduction:

Acetylcholine act as a neurotransmitter which means it sends messages or chemicals from one cell to another cell of the body. Acetylcholinesterase helps in stopping the excitation of a nerve cell after the transmission of impulse or in other words, we can say that this enzyme causes rapid hydrolysis of acetylcholine.

Interpretation Introduction

(c)

Interpretation:

Whether the allosteric transition be accounted for the MWC concerted mode or not needs to be explained.

Concept introduction:

Acetylcholine acts as a neurotransmitter which means, it sends messages or chemicals from one cell to another cell of the body. Acetylcholinesterase helps in stopping the excitation of a nerve cell after the transmission of impulse or in other words, one can say that this enzyme causes rapid hydrolysis of acetylcholine.

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Answer 5

Chapter 13, Problem 22P

Interpretation Introduction

(a)

Interpretation:

The factor by which an open to closed ratio increases by the binding of the firstacetylcholine molecule and the second acetylcholine molecule needs to be explained.

Concept introduction:

Acetylcholine act as a neurotransmitter which means, it sends messages or chemicals from one cell to another cell of the body. Acetylcholinesterase helps in stopping the excitation of a nerve cell after the transmission of impulse. In other words, this enzyme causes rapid hydrolysis of acetylcholine.

Interpretation Introduction

(b)

Interpretation:

The corresponding free energy contribution of the channel at 250C needs to be determined.

Concept introduction:

Acetylcholine act as a neurotransmitter which means it sends messages or chemicals from one cell to another cell of the body. Acetylcholinesterase helps in stopping the excitation of a nerve cell after the transmission of impulse or in other words, we can say that this enzyme causes rapid hydrolysis of acetylcholine.

Interpretation Introduction

(c)

Interpretation:

Whether the allosteric transition be accounted for the MWC concerted mode or not needs to be explained.

Concept introduction:

Acetylcholine acts as a neurotransmitter which means, it sends messages or chemicals from one cell to another cell of the body. Acetylcholinesterase helps in stopping the excitation of a nerve cell after the transmission of impulse or in other words, one can say that this enzyme causes rapid hydrolysis of acetylcholine.

Answer 6

Chapter 13, Problem 22P

Interpretation Introduction

(a)

Interpretation:

The factor by which an open to closed ratio increases by the binding of the firstacetylcholine molecule and the second acetylcholine molecule needs to be explained.

Concept introduction:

Acetylcholine act as a neurotransmitter which means, it sends messages or chemicals from one cell to another cell of the body. Acetylcholinesterase helps in stopping the excitation of a nerve cell after the transmission of impulse. In other words, this enzyme causes rapid hydrolysis of acetylcholine.

Answer 7

Chapter 13, Problem 22P

Interpretation Introduction

(a)

Interpretation:

The factor by which an open to closed ratio increases by the binding of the firstacetylcholine molecule and the second acetylcholine molecule needs to be explained.

Concept introduction:

Acetylcholine act as a neurotransmitter which means, it sends messages or chemicals from one cell to another cell of the body. Acetylcholinesterase helps in stopping the excitation of a nerve cell after the transmission of impulse. In other words, this enzyme causes rapid hydrolysis of acetylcholine.

Answer 8

Interpretation Introduction

(b)

Interpretation:

The corresponding free energy contribution of the channel at 250C needs to be determined.

Concept introduction:

Acetylcholine act as a neurotransmitter which means it sends messages or chemicals from one cell to another cell of the body. Acetylcholinesterase helps in stopping the excitation of a nerve cell after the transmission of impulse or in other words, we can say that this enzyme causes rapid hydrolysis of acetylcholine.

Answer 9

Interpretation Introduction

(b)

Interpretation:

The corresponding free energy contribution of the channel at 250C needs to be determined.

Concept introduction:

Acetylcholine act as a neurotransmitter which means it sends messages or chemicals from one cell to another cell of the body. Acetylcholinesterase helps in stopping the excitation of a nerve cell after the transmission of impulse or in other words, we can say that this enzyme causes rapid hydrolysis of acetylcholine.

Answer 10

Interpretation Introduction

(c)

Interpretation:

Whether the allosteric transition be accounted for the MWC concerted mode or not needs to be explained.

Concept introduction:

Acetylcholine acts as a neurotransmitter which means, it sends messages or chemicals from one cell to another cell of the body. Acetylcholinesterase helps in stopping the excitation of a nerve cell after the transmission of impulse or in other words, one can say that this enzyme causes rapid hydrolysis of acetylcholine.

Answer 11

Interpretation Introduction

(c)

Interpretation:

Whether the allosteric transition be accounted for the MWC concerted mode or not needs to be explained.

Concept introduction:

Acetylcholine acts as a neurotransmitter which means, it sends messages or chemicals from one cell to another cell of the body. Acetylcholinesterase helps in stopping the excitation of a nerve cell after the transmission of impulse or in other words, one can say that this enzyme causes rapid hydrolysis of acetylcholine.

Answer 12

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Answer 13

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Answer 14

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Answer 15

Ch. 13 - Prob. 1P Ch. 13 - Prob. 2P Ch. 13 - Prob. 3P Ch. 13 - Prob. 4P Ch. 13 - Prob. 5P Ch. 13 - Prob. 6P Ch. 13 - Prob. 7P Ch. 13 - Prob. 8P Ch. 13 - Prob. 9P Ch. 13 - Prob. 10P

Solution Summary: The author explains how an open to closed ratio increases by the binding of the first and second acetylcholine molecules.

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Chapter 13 Solutions