The time taken by the DNA polymerase to complete the replication process of the entire DNA molecule of the shortest chromosome, by moving uninterruptedly from one end to the other end. Also figure out whether DNA replication involves one starting point or follows an alternate hypothesis. Given: The DNA polymerase proceeds uninterruptedly on the DNA strand, from one end to the other end to synthesize the new DNA strand. Addition of nucleotides on the new DNA strand occurs at the rate of 50 base pairs per second (bp/s). The replication is limited to the S or the synthesis phase of the cell cycle. The shortest chromosome is 21 st chromosome in humans and its length is 50 × 10 6 bps. Introduction: The division of cells in a cell cycle involves two phases: interphase and mitotic phase. Replication of the genetic material takes place during synthesis phase or S phase of the interphase. DNA polymerase is responsible for DNA replication in both eukaryotes and prokaryotes.

Question

Want to see more full solutions like this?

Answer 1

Question

Chapter 13, Problem 1Q

Summary Introduction

To analyze:

The time taken by the DNA polymerase to complete the replication process of the entire DNA molecule of the shortest chromosome, by moving uninterruptedly from one end to the other end. Also figure out whether DNA replication involves one starting point or follows an alternate hypothesis.

Given:

The DNA polymerase proceeds uninterruptedly on the DNA strand, from one end to the other end to synthesize the new DNA strand. Addition of nucleotides on the new DNA strand occurs at the rate of 50 base pairs per second (bp/s). The replication is limited to the S or the synthesis phase of the cell cycle. The shortest chromosome is 21^st chromosome in humans and its length is 50×106 bps.

Introduction:

The division of cells in a cell cycle involves two phases: interphase and mitotic phase. Replication of the genetic material takes place during synthesis phase or S phase of the interphase. DNA polymerase is responsible for DNA replication in both eukaryotes and prokaryotes.

Expert Solution & Answer

Explanation of Solution

The rate at which DNA polymerase proceeds the formation of new DNA strand is 50 bp/s. Therefore, to replicate a DNA strand of 50×106 bps, the enzyme DNA polymerase will take 10⁶ seconds, which is approximately 278 hours.

The synthesis phase of a mammalian cell is 8 hours long, and the entire replication process occurs during this time. This indicates that there must be multiple DNA polymerase complexes involved in this process. Hence more than one replication origin sites must be there, where the enzyme would attach itself to synthesize a new strand.

Conclusion

Therefore, it can be concluded that there are many replication origin sites where DNA polymerase enzyme work simultaneously, to complete the synthesis of new DNA strand.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Students have asked these similar questions

19. On the diagram below a. Label the three pictures as: DNA; polypeptide; or RNA. b. Label the arrows as: translation or transcription/RNA processing. c. Add the following details to the diagram. Promoter region TATA box Transcription start site Transcription terminator Intron (A,B,C,D) Exons (1,2,3,4,5) Splice sites 5' cap 5' UTR (untranslated region) 3' poly A tail 3' UTR (untranslated region) Translational start (AUG) Translational stop (UGA, UAG, or UAA) N and C ends of polypeptide 0000

Match the letter labels in the figure below to the terms. Some letter labels are not used. MNNNNNNIN M C B A M D F E H K G 8

The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions. 1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction? 2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe: a) What molecule do you recommend for the trial. Why? b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for? 3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale. 4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale. Mutation 1 Mutation 2

Answer 2

Question

Chapter 13, Problem 1Q

Summary Introduction

To analyze:

The time taken by the DNA polymerase to complete the replication process of the entire DNA molecule of the shortest chromosome, by moving uninterruptedly from one end to the other end. Also figure out whether DNA replication involves one starting point or follows an alternate hypothesis.

Given:

The DNA polymerase proceeds uninterruptedly on the DNA strand, from one end to the other end to synthesize the new DNA strand. Addition of nucleotides on the new DNA strand occurs at the rate of 50 base pairs per second (bp/s). The replication is limited to the S or the synthesis phase of the cell cycle. The shortest chromosome is 21^st chromosome in humans and its length is 50×106 bps.

Introduction:

The division of cells in a cell cycle involves two phases: interphase and mitotic phase. Replication of the genetic material takes place during synthesis phase or S phase of the interphase. DNA polymerase is responsible for DNA replication in both eukaryotes and prokaryotes.

Expert Solution & Answer

Explanation of Solution

The rate at which DNA polymerase proceeds the formation of new DNA strand is 50 bp/s. Therefore, to replicate a DNA strand of 50×106 bps, the enzyme DNA polymerase will take 10⁶ seconds, which is approximately 278 hours.

The synthesis phase of a mammalian cell is 8 hours long, and the entire replication process occurs during this time. This indicates that there must be multiple DNA polymerase complexes involved in this process. Hence more than one replication origin sites must be there, where the enzyme would attach itself to synthesize a new strand.

Conclusion

Therefore, it can be concluded that there are many replication origin sites where DNA polymerase enzyme work simultaneously, to complete the synthesis of new DNA strand.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Answer 3

Question

Chapter 13, Problem 1Q

Summary Introduction

To analyze:

The time taken by the DNA polymerase to complete the replication process of the entire DNA molecule of the shortest chromosome, by moving uninterruptedly from one end to the other end. Also figure out whether DNA replication involves one starting point or follows an alternate hypothesis.

Given:

The DNA polymerase proceeds uninterruptedly on the DNA strand, from one end to the other end to synthesize the new DNA strand. Addition of nucleotides on the new DNA strand occurs at the rate of 50 base pairs per second (bp/s). The replication is limited to the S or the synthesis phase of the cell cycle. The shortest chromosome is 21^st chromosome in humans and its length is 50×106 bps.

Introduction:

The division of cells in a cell cycle involves two phases: interphase and mitotic phase. Replication of the genetic material takes place during synthesis phase or S phase of the interphase. DNA polymerase is responsible for DNA replication in both eukaryotes and prokaryotes.

Expert Solution & Answer

Explanation of Solution

The rate at which DNA polymerase proceeds the formation of new DNA strand is 50 bp/s. Therefore, to replicate a DNA strand of 50×106 bps, the enzyme DNA polymerase will take 10⁶ seconds, which is approximately 278 hours.

The synthesis phase of a mammalian cell is 8 hours long, and the entire replication process occurs during this time. This indicates that there must be multiple DNA polymerase complexes involved in this process. Hence more than one replication origin sites must be there, where the enzyme would attach itself to synthesize a new strand.

Conclusion

Therefore, it can be concluded that there are many replication origin sites where DNA polymerase enzyme work simultaneously, to complete the synthesis of new DNA strand.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Answer 4

Question

Chapter 13, Problem 1Q

Summary Introduction

To analyze:

The time taken by the DNA polymerase to complete the replication process of the entire DNA molecule of the shortest chromosome, by moving uninterruptedly from one end to the other end. Also figure out whether DNA replication involves one starting point or follows an alternate hypothesis.

Given:

The DNA polymerase proceeds uninterruptedly on the DNA strand, from one end to the other end to synthesize the new DNA strand. Addition of nucleotides on the new DNA strand occurs at the rate of 50 base pairs per second (bp/s). The replication is limited to the S or the synthesis phase of the cell cycle. The shortest chromosome is 21^st chromosome in humans and its length is 50×106 bps.

Introduction:

The division of cells in a cell cycle involves two phases: interphase and mitotic phase. Replication of the genetic material takes place during synthesis phase or S phase of the interphase. DNA polymerase is responsible for DNA replication in both eukaryotes and prokaryotes.

Expert Solution & Answer

Explanation of Solution

The rate at which DNA polymerase proceeds the formation of new DNA strand is 50 bp/s. Therefore, to replicate a DNA strand of 50×106 bps, the enzyme DNA polymerase will take 10⁶ seconds, which is approximately 278 hours.

The synthesis phase of a mammalian cell is 8 hours long, and the entire replication process occurs during this time. This indicates that there must be multiple DNA polymerase complexes involved in this process. Hence more than one replication origin sites must be there, where the enzyme would attach itself to synthesize a new strand.

Conclusion

Therefore, it can be concluded that there are many replication origin sites where DNA polymerase enzyme work simultaneously, to complete the synthesis of new DNA strand.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Answer 5

Chapter 13, Problem 1Q

Summary Introduction

To analyze:

The time taken by the DNA polymerase to complete the replication process of the entire DNA molecule of the shortest chromosome, by moving uninterruptedly from one end to the other end. Also figure out whether DNA replication involves one starting point or follows an alternate hypothesis.

Given:

The DNA polymerase proceeds uninterruptedly on the DNA strand, from one end to the other end to synthesize the new DNA strand. Addition of nucleotides on the new DNA strand occurs at the rate of 50 base pairs per second (bp/s). The replication is limited to the S or the synthesis phase of the cell cycle. The shortest chromosome is 21^st chromosome in humans and its length is 50×106 bps.

Introduction:

The division of cells in a cell cycle involves two phases: interphase and mitotic phase. Replication of the genetic material takes place during synthesis phase or S phase of the interphase. DNA polymerase is responsible for DNA replication in both eukaryotes and prokaryotes.

Expert Solution & Answer

Explanation of Solution

The rate at which DNA polymerase proceeds the formation of new DNA strand is 50 bp/s. Therefore, to replicate a DNA strand of 50×106 bps, the enzyme DNA polymerase will take 10⁶ seconds, which is approximately 278 hours.

The synthesis phase of a mammalian cell is 8 hours long, and the entire replication process occurs during this time. This indicates that there must be multiple DNA polymerase complexes involved in this process. Hence more than one replication origin sites must be there, where the enzyme would attach itself to synthesize a new strand.

Conclusion

Therefore, it can be concluded that there are many replication origin sites where DNA polymerase enzyme work simultaneously, to complete the synthesis of new DNA strand.

Answer 6

Chapter 13, Problem 1Q

Summary Introduction

To analyze:

The time taken by the DNA polymerase to complete the replication process of the entire DNA molecule of the shortest chromosome, by moving uninterruptedly from one end to the other end. Also figure out whether DNA replication involves one starting point or follows an alternate hypothesis.

Given:

The DNA polymerase proceeds uninterruptedly on the DNA strand, from one end to the other end to synthesize the new DNA strand. Addition of nucleotides on the new DNA strand occurs at the rate of 50 base pairs per second (bp/s). The replication is limited to the S or the synthesis phase of the cell cycle. The shortest chromosome is 21^st chromosome in humans and its length is 50×106 bps.

Introduction:

The division of cells in a cell cycle involves two phases: interphase and mitotic phase. Replication of the genetic material takes place during synthesis phase or S phase of the interphase. DNA polymerase is responsible for DNA replication in both eukaryotes and prokaryotes.

Expert Solution & Answer

Explanation of Solution

The rate at which DNA polymerase proceeds the formation of new DNA strand is 50 bp/s. Therefore, to replicate a DNA strand of 50×106 bps, the enzyme DNA polymerase will take 10⁶ seconds, which is approximately 278 hours.

The synthesis phase of a mammalian cell is 8 hours long, and the entire replication process occurs during this time. This indicates that there must be multiple DNA polymerase complexes involved in this process. Hence more than one replication origin sites must be there, where the enzyme would attach itself to synthesize a new strand.

Conclusion

Therefore, it can be concluded that there are many replication origin sites where DNA polymerase enzyme work simultaneously, to complete the synthesis of new DNA strand.

Answer 7

Chapter 13, Problem 1Q

Summary Introduction

To analyze:

The time taken by the DNA polymerase to complete the replication process of the entire DNA molecule of the shortest chromosome, by moving uninterruptedly from one end to the other end. Also figure out whether DNA replication involves one starting point or follows an alternate hypothesis.

Given:

The DNA polymerase proceeds uninterruptedly on the DNA strand, from one end to the other end to synthesize the new DNA strand. Addition of nucleotides on the new DNA strand occurs at the rate of 50 base pairs per second (bp/s). The replication is limited to the S or the synthesis phase of the cell cycle. The shortest chromosome is 21^st chromosome in humans and its length is 50×106 bps.

Introduction:

The division of cells in a cell cycle involves two phases: interphase and mitotic phase. Replication of the genetic material takes place during synthesis phase or S phase of the interphase. DNA polymerase is responsible for DNA replication in both eukaryotes and prokaryotes.

Answer 8

Expert Solution & Answer

Explanation of Solution

The rate at which DNA polymerase proceeds the formation of new DNA strand is 50 bp/s. Therefore, to replicate a DNA strand of 50×106 bps, the enzyme DNA polymerase will take 10⁶ seconds, which is approximately 278 hours.

The synthesis phase of a mammalian cell is 8 hours long, and the entire replication process occurs during this time. This indicates that there must be multiple DNA polymerase complexes involved in this process. Hence more than one replication origin sites must be there, where the enzyme would attach itself to synthesize a new strand.

Answer 9

Expert Solution & Answer

Answer 10

Expert Solution & Answer

Answer 11

Conclusion

Therefore, it can be concluded that there are many replication origin sites where DNA polymerase enzyme work simultaneously, to complete the synthesis of new DNA strand.

Answer 12

Ch. 13.1 - Prob. 1R Ch. 13.1 - Prob. 2R Ch. 13.1 - Prob. 3R Ch. 13.1 - Prob. 4R Ch. 13.2 - Prob. 1R Ch. 13.2 - Prob. 2R Ch. 13.2 - Prob. 3R Ch. 13.3 - Prob. 1R Ch. 13.3 - Prob. 2R Ch. 13.3 - Prob. 3R

Concept explainers

Videos

Explanation of Solution

Want to see more full solutions like this?

Chapter 13 Solutions