Biology 2e
2nd Edition
ISBN: 9781947172517
Author: Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher: OpenStax
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Chapter 13, Problem 12RQ
Abnormalities in the number of X chromosomes tends to have milder
- deletions
- nonhomologous recombination
- synapsis
- X inactivation
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Molecular Biology
A-C components of the question are corresponding to attached image labeled 1.
D component of the question is corresponding to attached image labeled 2.
For a eukaryotic mRNA, the sequences is as follows where AUGrepresents the start codon, the yellow is the Kozak sequence and (XXX) just represents any codonfor an amino acid (no stop codons here). G-cap and polyA tail are not shown
A. How long is the peptide produced?B. What is the function (a sentence) of the UAA highlighted in blue?C. If the sequence highlighted in blue were changed from UAA to UAG, how would that affecttranslation?
D. (1) The sequence highlighted in yellow above is moved to a new position indicated below. Howwould that affect translation? (2) How long would be the protein produced from this new mRNA?
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Explain why the cell doesn’t need 61 tRNAs (one for each codon).
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You discover a disease causing mutation (indicated by the arrow) that alters splicing of its mRNA. This mutation (a base substitution in the splicing sequence) eliminates a 3’ splice site resulting in the inclusion of the second intron (I2) in the final mRNA. We are going to pretend that this intron is short having only 15 nucleotides (most introns are much longer so this is just to make things simple) with the following sequence shown below in bold. The ( ) indicate the reading frames in the exons; the included intron 2 sequences are in bold.
A. Would you expected this change to be harmful? ExplainB. If you were to do gene therapy to fix this problem, briefly explain what type of gene therapy youwould use to correct this.
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Chapter 13 Solutions
Biology 2e
Ch. 13 - Figure 13.3 In a test cross for two...Ch. 13 - Figure 13.4 Which of the following statements is...Ch. 13 - Figure 13.6 Which of the following statements...Ch. 13 - X-linked recessive traits in humans (or in...Ch. 13 - The first suggestion that chromosomes may...Ch. 13 - Which recombination frequency corresponds to...Ch. 13 - Which recombination frequency corresponds to...Ch. 13 - Which of the following codes describes position 12...Ch. 13 - In agriculture, polyploid crops (like coffee,...Ch. 13 - Assume a pericentric inversion occurred in one of...
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