EBK LIFE: THE SCIENCE OF BIOLOGY
EBK LIFE: THE SCIENCE OF BIOLOGY
11th Edition
ISBN: 8220103935432
Author: Sadava
Publisher: MAC HIGHER
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Chapter 12.6, Problem 2R
Summary Introduction

To review:

The outcome of plasmid that undergoes integration with the prokaryote’s chromosomal deoxyribonucleic acid (DNA).

Introduction:

Plasmid incorporation in the bacterium by conjugation gives a capability to the bacterium, to acquire antibiotic resistance genes, xenobiotics degradation genes, as well as conjugative ability. Sometimes, this plasmid by the virtue of homology between chromosomal and plasmid genes can undergo recombination and integration with the chromosomal DNA of the prokaryote. These molecules when undergoing conjugation with other bacterium leads to transfer of plasmid genes along with chromosomal genes in that recipient bacteria.

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*Example 2: Tracing the path of an autosomal dominant trait Trait: Neurofibromatosis Forms of the trait: The dominant form is neurofibromatosis, caused by the production of an abnormal form of the protein neurofibromin. Affected individuals show spots of abnormal skin pigmentation and non-cancerous tumors that can interfere with the nervous system and cause blindness. Some tumors can convert to a cancerous form. i The recessive form is a normal protein - in other words, no neurofibromatosis.moovi A typical pedigree for a family that carries neurofibromatosis is shown below. Note that carriers are not indicated with half-colored shapes in this chart. Use the letter "N" to indicate the dominant neurofibromatosis allele, and the letter "n" for the normal allele. Nn nn nn 2 nn Nn A 3 N-
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