The effect on DNA replication of mutations that destroyed 3 ′ → 5 ′ exonuclease activity of DNA polymerase I. Introduction: A change in the genetic code during replication is termed as “mutation”. Mutation can occur during replication or recombination. It is a permanent alteration in the nucleotide sequence in DNA . Cells have evolved many “repair mechanisms” due to the lethal potential of DNA mutations. Mutation that can mutate damaged DNA are, “substitution”, “deletion” or “insertion” of base pairs.

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Answer 1

Question

Chapter 12.3, Problem 27AQP

a.

Summary Introduction

To determine:

The effect on DNA replication of mutations that destroyed 3′ → 5′ exonuclease activity of DNA polymerase I.

Introduction:

A change in the genetic code during replication is termed as “mutation”. Mutation can occur during replication or recombination. It is a permanent alteration in the nucleotide sequence in DNA. Cells have evolved many “repair mechanisms” due to the lethal potential of DNA mutations. Mutation that can mutate damaged DNA are, “substitution”, “deletion” or “insertion” of base pairs.

b.

Summary Introduction

To determine:

The effect on DNA replication of mutations that destroyed 5′ → 3′ exonuclease activity of DNA polymerase I.

c.

Summary Introduction

To determine:

The effect on DNA replication of mutations that destroyed 5′ → 3′ polymerase activity of DNA polymerase I.

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Answer 2

Question

Chapter 12.3, Problem 27AQP

a.

Summary Introduction

To determine:

The effect on DNA replication of mutations that destroyed 3′ → 5′ exonuclease activity of DNA polymerase I.

Introduction:

A change in the genetic code during replication is termed as “mutation”. Mutation can occur during replication or recombination. It is a permanent alteration in the nucleotide sequence in DNA. Cells have evolved many “repair mechanisms” due to the lethal potential of DNA mutations. Mutation that can mutate damaged DNA are, “substitution”, “deletion” or “insertion” of base pairs.

b.

Summary Introduction

To determine:

The effect on DNA replication of mutations that destroyed 5′ → 3′ exonuclease activity of DNA polymerase I.

c.

Summary Introduction

To determine:

The effect on DNA replication of mutations that destroyed 5′ → 3′ polymerase activity of DNA polymerase I.

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See solution

Answer 3

Question

Chapter 12.3, Problem 27AQP

a.

Summary Introduction

To determine:

The effect on DNA replication of mutations that destroyed 3′ → 5′ exonuclease activity of DNA polymerase I.

Introduction:

A change in the genetic code during replication is termed as “mutation”. Mutation can occur during replication or recombination. It is a permanent alteration in the nucleotide sequence in DNA. Cells have evolved many “repair mechanisms” due to the lethal potential of DNA mutations. Mutation that can mutate damaged DNA are, “substitution”, “deletion” or “insertion” of base pairs.

b.

Summary Introduction

To determine:

The effect on DNA replication of mutations that destroyed 5′ → 3′ exonuclease activity of DNA polymerase I.

c.

Summary Introduction

To determine:

The effect on DNA replication of mutations that destroyed 5′ → 3′ polymerase activity of DNA polymerase I.

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Answer 4

Question

Chapter 12.3, Problem 27AQP

a.

Summary Introduction

To determine:

The effect on DNA replication of mutations that destroyed 3′ → 5′ exonuclease activity of DNA polymerase I.

Introduction:

A change in the genetic code during replication is termed as “mutation”. Mutation can occur during replication or recombination. It is a permanent alteration in the nucleotide sequence in DNA. Cells have evolved many “repair mechanisms” due to the lethal potential of DNA mutations. Mutation that can mutate damaged DNA are, “substitution”, “deletion” or “insertion” of base pairs.

b.

Summary Introduction

To determine:

The effect on DNA replication of mutations that destroyed 5′ → 3′ exonuclease activity of DNA polymerase I.

c.

Summary Introduction

To determine:

The effect on DNA replication of mutations that destroyed 5′ → 3′ polymerase activity of DNA polymerase I.

Expert Solution & Answer

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Answer 5

Chapter 12.3, Problem 27AQP

a.

Summary Introduction

To determine:

The effect on DNA replication of mutations that destroyed 3′ → 5′ exonuclease activity of DNA polymerase I.

Introduction:

A change in the genetic code during replication is termed as “mutation”. Mutation can occur during replication or recombination. It is a permanent alteration in the nucleotide sequence in DNA. Cells have evolved many “repair mechanisms” due to the lethal potential of DNA mutations. Mutation that can mutate damaged DNA are, “substitution”, “deletion” or “insertion” of base pairs.

b.

Summary Introduction

To determine:

The effect on DNA replication of mutations that destroyed 5′ → 3′ exonuclease activity of DNA polymerase I.

c.

Summary Introduction

To determine:

The effect on DNA replication of mutations that destroyed 5′ → 3′ polymerase activity of DNA polymerase I.

Answer 6

Chapter 12.3, Problem 27AQP

a.

Summary Introduction

To determine:

The effect on DNA replication of mutations that destroyed 3′ → 5′ exonuclease activity of DNA polymerase I.

Introduction:

A change in the genetic code during replication is termed as “mutation”. Mutation can occur during replication or recombination. It is a permanent alteration in the nucleotide sequence in DNA. Cells have evolved many “repair mechanisms” due to the lethal potential of DNA mutations. Mutation that can mutate damaged DNA are, “substitution”, “deletion” or “insertion” of base pairs.

Answer 7

Chapter 12.3, Problem 27AQP

a.

Summary Introduction

To determine:

The effect on DNA replication of mutations that destroyed 3′ → 5′ exonuclease activity of DNA polymerase I.

Introduction:

A change in the genetic code during replication is termed as “mutation”. Mutation can occur during replication or recombination. It is a permanent alteration in the nucleotide sequence in DNA. Cells have evolved many “repair mechanisms” due to the lethal potential of DNA mutations. Mutation that can mutate damaged DNA are, “substitution”, “deletion” or “insertion” of base pairs.

Answer 8

b.

Summary Introduction

To determine:

The effect on DNA replication of mutations that destroyed 5′ → 3′ exonuclease activity of DNA polymerase I.

Answer 9

b.

Summary Introduction

To determine:

The effect on DNA replication of mutations that destroyed 5′ → 3′ exonuclease activity of DNA polymerase I.

Answer 10

c.

Summary Introduction

To determine:

The effect on DNA replication of mutations that destroyed 5′ → 3′ polymerase activity of DNA polymerase I.

Answer 11

c.

Summary Introduction

To determine:

The effect on DNA replication of mutations that destroyed 5′ → 3′ polymerase activity of DNA polymerase I.

Answer 12

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Answer 13

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Answer 14

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Answer 15

Ch. 12.2 - Prob. 1CC Ch. 12.2 - Prob. 1COQ Ch. 12.2 - Prob. 20AQP Ch. 12.2 - Prob. 21AQP Ch. 12.2 - Prob. 22AQP Ch. 12.2 - Prob. 23AQP Ch. 12.2 - Prob. 24AQP Ch. 12.2 - Prob. 2CC Ch. 12.2 - Prob. 2COQ Ch. 12.2 - Prob. 3CC

To determine: The effect on DNA replication of mutations that destroyed 5′ → 3′ exonuclease activity of DNA polymerase I.

To determine: The effect on DNA replication of mutations that destroyed 5′ → 3′ polymerase activity of DNA polymerase I.

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Chapter 12 Solutions

To determine:

The effect on DNA replication of mutations that destroyed 5′ → 3′ exonuclease activity of DNA polymerase I.

To determine:

The effect on DNA replication of mutations that destroyed 5′ → 3′ polymerase activity of DNA polymerase I.