Lab Manual to accompany McKinley's Anatomy & Physiology Main Version
4th Edition
ISBN: 9781264265565
Author: McKinley, Michael
Publisher: MCGRAW-HILL HIGHER EDUCATION
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Chapter 12.10, Problem 31WDYL
Summary Introduction
To determine:
The action of nitric oxide as a neuromodulator.
Concept introduction:
The release of various chemicals from the cell that alters or regulate the response of neurons to neurotransmitters. The substances that alter the response of neurons are called as neurotransmitters and the process is called as neuromodulation. For example, some neuromodulators are nitric oxide and endocannabinoids.
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19. On the diagram below
a. Label the three pictures as: DNA; polypeptide; or RNA.
b. Label the arrows as: translation or transcription/RNA processing.
c. Add the following details to the diagram.
Promoter region
TATA box
Transcription start site
Transcription terminator
Intron (A,B,C,D)
Exons (1,2,3,4,5)
Splice sites
5' cap
5' UTR (untranslated region)
3' poly A tail
3' UTR (untranslated region)
Translational start (AUG)
Translational stop (UGA, UAG, or UAA)
N and C ends of polypeptide
0000
Match the letter labels in the figure below to the terms. Some letter
labels are not used.
MNNNNNNIN
M
C
B
A
M
D
F
E
H
K
G
8
The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions.
1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction?
2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe:
a) What molecule do you recommend for the trial. Why?
b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for?
3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale.
4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale.
Mutation 1
Mutation 2
Chapter 12 Solutions
Lab Manual to accompany McKinley's Anatomy & Physiology Main Version
Ch. 12.1 - Prob. 1WDYLCh. 12.1 - Prob. 2WDYLCh. 12.1 - Prob. 3WDYLCh. 12.2 - Prob. 4WDYLCh. 12.2 - Prob. 5WDYLCh. 12.2 - Prob. 6WDYLCh. 12.2 - Prob. 7WDYLCh. 12.2 - Prob. 8WDYLCh. 12.3 - Prob. 9WDYLCh. 12.4 - If a person has a brain tumor, is it more likely...
Ch. 12.4 - Prob. 11WDYLCh. 12.4 - Prob. 12WDYLCh. 12.4 - Prob. 13WDYLCh. 12.5 - Prob. 14WDYLCh. 12.5 - Prob. 15WDYLCh. 12.6 - Prob. 16WDYLCh. 12.6 - Prob. 17WDYLCh. 12.7 - Prob. 18WDYLCh. 12.7 - Prob. 19WDYLCh. 12.7 - Prob. 20WDYLCh. 12.8 - How are EPSP and IPSP graded potentials...Ch. 12.8 - Prob. 22WDYLCh. 12.8 - How does depolarization and repolarization occur...Ch. 12.8 - Prob. 24WDYLCh. 12.8 - Prob. 25WDYLCh. 12.9 - Prob. 26WDYLCh. 12.9 - Prob. 27WDYLCh. 12.9 - Prob. 28WDYLCh. 12.10 - Prob. 29WDYLCh. 12.10 - Prob. 30WDYLCh. 12.10 - Prob. 31WDYLCh. 12.11 - Prob. 32WDYLCh. 12.11 - Prob. 33WDYLCh. 12 - Prob. 1DYKBCh. 12 - Prob. 2DYKBCh. 12 - Prob. 3DYKBCh. 12 - Prob. 4DYKBCh. 12 - Prob. 5DYKBCh. 12 - Prob. 6DYKBCh. 12 - _____ 7. An action potential is generated when...Ch. 12 - Prob. 8DYKBCh. 12 - Prob. 9DYKBCh. 12 - Prob. 10DYKBCh. 12 - What are the four structural types of neurons? How...Ch. 12 - Prob. 12DYKBCh. 12 - How does myelination differ between the CNS and...Ch. 12 - Describe the procedure by which a PNS axon may...Ch. 12 - Prob. 15DYKBCh. 12 - Prob. 16DYKBCh. 12 - Explain summation of EPSPs and IPSPs and the...Ch. 12 - Graph and explain the events associated with an...Ch. 12 - Prob. 19DYKBCh. 12 - Prob. 20DYKBCh. 12 - Prob. 1CALCh. 12 - Prob. 2CALCh. 12 - Prob. 3CALCh. 12 - Prob. 4CALCh. 12 - Sarah wants to call her new friend Julie and needs...Ch. 12 - Over a period of 6 to 9 months, Marianne began to...Ch. 12 - Prob. 2CSLCh. 12 - Prob. 3CSL
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