RESEARCH METHODS F/ BEHAV.(LL)-W/MINTAP
6th Edition
ISBN: 9781337755016
Author: GRAVETTER
Publisher: CENGAGE L
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Chapter 12.1, Problem 1LO
Define the goal or purpose of the
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In a crossover trial comparing a new drug to a standard, π denotes the probabilitythat the new one is judged better. It is desired to estimate π and test H0 : π = 0.5against H1 : π = 0.5. In 20 independent observations, the new drug is better eachtime.(a) Find and plot the likelihood function. Give the ML estimate of π (Hint: youmay use the plot function in R)
Can you explain what this analysis means in layman's terms?
- We calculated that a target sample size of 3626, which was based on anticipated baseline 90-day mortality of 22% and a noninferiority margin of no more than 4 percentage points, would give the trial 80% power, at a one-sided alpha level of 2.5%, accounting for a maximum of 5% loss to follow-up and for early stopping rules for three interim analyses.-
Can you help me understand this analysis?
A 95.7% confidence interval is shown for the intention-to-treat analysis (accounting for alpha spending in interim analyses), and 95% confidence intervals are shown for the other two analyses. The widths of the confidence intervals have not been adjusted for multiplicity. The dashed line indicates the noninferiority margin of 4 percentage points.
Chapter 12 Solutions
RESEARCH METHODS F/ BEHAV.(LL)-W/MINTAP
Ch. 12.1 - Define the goal or purpose of the correlational...Ch. 12.2 - Prob. 2LOCh. 12.2 - Identify the statistical procedure used to...Ch. 12.3 - Describe how correlations are used for prediction,...Ch. 12.4 - Prob. 5LOCh. 12 - In addition to the key words, you should also be...Ch. 12 - Explain how the purpose of a correctional study...Ch. 12 - Each of the following studies examines the...Ch. 12 - Describe the pattern that would appear in a...Ch. 12 - Suppose that there is a negative relationship...
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