ORGANIC CHEMISTRY (LL)-W/WILEYPLUS
ORGANIC CHEMISTRY (LL)-W/WILEYPLUS
4th Edition
ISBN: 9781119659556
Author: Klein
Publisher: WILEY
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Chapter 12, Problem 54ASP
Interpretation Introduction

Interpretation:

The compound which does not give 2methyl2pentanol by using Grignard reagent is to be determined.

Concept introduction:

When a Grignard reagent reacts with a carbonyl compound, the alkyl part of the reagent acts as a nucleophile and attacks the electrophilic carbonyl carbon, forming an intermediate compound. This after an acidic aqueous workup yields the product, generally alcohol, depending on the starting carbonyl compound used. The basicity of the Grignard reagent plays an important role in the kinetics and yield of the reaction.

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For each reaction below, decide if the first stable organic product that forms in solution will create a new CC bond, and check the appropriate box. Next, for each reaction to which you answered "Yes" to in the table, draw this product in the drawing area below. Note for advanced students: for this problem, don't worry if you think this product will continue to react under the current conditions - just focus on the first stable product you expect to form in solution. ? Will the first MgBr product that forms in this reaction create a new CC bond? olo ? OH جمله O Yes Ⓒ No MgCl ? Will the first product that forms in this reaction create a new CC bond? Click and drag to start drawing a structure. Yes No X ☐ : ☐ टे PH
Assign all the protons
PROPOSE REACTION MECHANISM FOR ACID-CATALYZED REACTION OF 3-PENTANONE WITH DIMETHYLAMINE
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