Chapter 12, Problem 34SAE

Summary Introduction

To review:

The impact of lack of memory B cells (lymphocytes maturing in the bone marrow) for a particular antigen on the type of humoral response (primary or secondary).

Introduction:

Humoral immunity is mediated by antibodies or macromolecules present in extracellular fluid. It is named so due to the substances involved in humors (body fluids). B lymphocytes also help in overseeing the humoral immunity. The primary function of these cells is to identify and remember specific antigens. The humoral response is divided into two types, namely, primary and secondary. The primary immune response occurs when an antigen encounters immune system for the first time leading to antigen recognition and raising antibody and producing memory lymphocytes. The secondary immune response occurs when an antigen encounters immune system for the second and more time when exposed to the same antigen.