Chapter 12, Problem 12A.1DQ

Interpretation Introduction

Interpretation:

The reasons as to why spectrometers that operate at the highest available fields and frequencies are used to determine the structure of macromolecules in NMR spectroscopy has to be stated.

Concept introduction:

The NMR frequency of a given molecule depends upon its nuclear environment.  The chemical shift of a nucleus is the difference between its resonance frequency and that of a reference standard.  The standard for ${}^1\text{H}$ and ${}^{13}\text{C}$ is trimethylsilane, known as TMS.