Biochemistry
8th Edition
ISBN: 9781285429106
Author: Campbell, Mary K., FARRELL, Shawn O.
Publisher: Cengage Learning,
expand_more
expand_more
format_list_bulleted
Concept explainers
Videos
Question
Chapter 11, Problem 76RE
Interpretation Introduction
Interpretation:
The term “epigenetics” is to be defined.
Concept introduction:
The enzymes with no protein are known as the ribozymes.
The epigenome is related to the sum total of all the changes that take place in the DNA and the chromatin in an organism that are not directly linked to the changes in the sequence of the bases.
Expert Solution & Answer
Trending nowThis is a popular solution!
Students have asked these similar questions
Please draw out the molecular structures of each molecule and show how each enzyme + cofactor would affect the following molecule in the human metabolic pathway.
(This is a metabolic map)
Please draw out the molecular structures of each molecule and show how an enzyme + cofactor would affect the following molecule in the human metabolic pathway to create energy.
Please draw out the molecular structures of each molecule and show how each enzyme + cofactor would affect the following molecule in the human metabolic pathway.
Chapter 11 Solutions
Biochemistry
Ch. 11 - RECALL What is the difference in the requirement...Ch. 11 - RECALL List three important properties of RNA...Ch. 11 - RECALL What is the subunit composition of E. coli...Ch. 11 - RECALL What is the difference between the core...Ch. 11 - RECALL What are the different terms used to...Ch. 11 - Prob. 6RECh. 11 - RECALL Put the following in linear order: UP...Ch. 11 - RECALL Distinguish between rho-dependent...Ch. 11 - REFLECT AND APPLY Diagram a section of DNA being...Ch. 11 - Prob. 10RE
Ch. 11 - RECALL What is a s factor? Why is it important in...Ch. 11 - RECALL What is the difference between 70 and 32?Ch. 11 - RECALL What is the function of the catabolite...Ch. 11 - RECALL What is transcription attenuation?Ch. 11 - REFLECT AND APPLY What role does an operon play in...Ch. 11 - Prob. 16RECh. 11 - REFLECT AND APPLY Give an example of a system in...Ch. 11 - Prob. 18RECh. 11 - BIOCHEMICAL CONNECTIONS What is an aptamer?Ch. 11 - BIOCHEMICAL CONNECTIONS What is a riboswitch?Ch. 11 - Prob. 21RECh. 11 - Prob. 22RECh. 11 - Prob. 23RECh. 11 - RECALL What are some of the main differences...Ch. 11 - RECALL What are the products of the reactions of...Ch. 11 - Prob. 26RECh. 11 - RECALL List the Pol II general transcription...Ch. 11 - REFLECT AND APPLY What are the functions of TFIIH?Ch. 11 - Prob. 29RECh. 11 - Prob. 30RECh. 11 - Prob. 31RECh. 11 - Prob. 32RECh. 11 - Prob. 33RECh. 11 - Prob. 34RECh. 11 - Prob. 35RECh. 11 - REFLECT AND APPLY Explain the relationship between...Ch. 11 - Prob. 37RECh. 11 - Prob. 38RECh. 11 - Prob. 39RECh. 11 - Prob. 40RECh. 11 - Prob. 41RECh. 11 - Prob. 42RECh. 11 - Prob. 43RECh. 11 - RECALL What are the two main circumstances...Ch. 11 - Prob. 45RECh. 11 - Prob. 46RECh. 11 - Prob. 47RECh. 11 - Prob. 48RECh. 11 - Prob. 49RECh. 11 - Prob. 50RECh. 11 - Prob. 51RECh. 11 - Prob. 52RECh. 11 - Prob. 53RECh. 11 - RECALL What is RNA interference?Ch. 11 - Prob. 55RECh. 11 - Prob. 56RECh. 11 - Prob. 57RECh. 11 - Prob. 58RECh. 11 - Prob. 59RECh. 11 - Prob. 60RECh. 11 - Prob. 61RECh. 11 - Prob. 62RECh. 11 - Prob. 63RECh. 11 - Prob. 64RECh. 11 - RECALL List several ways in which RNA is processed...Ch. 11 - Prob. 66RECh. 11 - REFLECT AND APPLY Why is a trimming process...Ch. 11 - REFLECT AND APPLY List three molecular changes...Ch. 11 - Prob. 69RECh. 11 - Prob. 70RECh. 11 - Prob. 71RECh. 11 - Prob. 72RECh. 11 - Prob. 73RECh. 11 - REFLECT AND APPLY Outline a mechanism by which RNA...Ch. 11 - REFLECT AND APPLY Why are proteins more effective...Ch. 11 - Prob. 76RECh. 11 - Prob. 77RECh. 11 - Prob. 78RECh. 11 - Prob. 79RECh. 11 - Prob. 80RE
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biochemistry and related others by exploring similar questions and additional content below.Similar questions
- Please draw out the mechanism with curved arrows showing electron flow. Pyruvate is accepted into the TCA cycle by a “feeder” reaction using the pyruvate dehydrogenase complex, resulting in acetyl-CoA and CO2. Provide the mechanism for this reaction utilizing the TPP cofactor. Include the roles of all cofactors.arrow_forwardPyruvate is accepted into the TCA cycle by a “feeder” reaction using the pyruvate dehydrogenase complex, resulting in acetyl-CoA and CO2. Provide the mechanism for this reaction utilizing the TPP cofactor. Include the roles of all cofactors.arrow_forwardThe mitochondrial ATP synthase has 10 copies of the F0 subunit “c”, and the [H ] in the mitochondrial inner membrane space (IMS) is 6.31 x 10-8 M and the [H + ] in the matrix is 3.16 x 10-9 M. Calculate the minimum membrane potential (∆Ψ) necessary to make ATP synthesis thermodynamically favorable. [Assume ∆G' ofphosphate hydrolysis of ATP is - 45 kJ/mol.]arrow_forward
- B- Vitamins are converted readily into important metabolic cofactors. Deficiency in any one of them has serious side effects. a. The disease beriberi results from a vitamin B 1 (Thiamine) deficiency and is characterized by cardiac and neurological symptoms. One key diagnostic for this disease is an increased level of pyruvate and α-ketoglutarate in the bloodstream. How does this vitamin deficiency lead to increased serumlevels of these factors? b. What would you expect the effect on the TCA intermediates for a patient suffering from vitamin B 5 deficiency? c. What would you expect the effect on the TCA intermediates for a patientsuffering from vitamin B 2 /B 3 deficiency?arrow_forwardPyruvate is accepted into the TCA cycle by a “feeder” reaction using the pyruvate dehydrogenase complex, resulting in acetyl-CoA and CO2. Provide a full mechanism for this reaction utilizing the TPP cofactor. Include the roles of all cofactors.arrow_forwardMap out all of the metabolic pathways in the liver cell. Draw out the structures and names of all compounds neatly by hand and the pathways responsible for metabolizing them. Some examples are: Glycolysis/gluconeogenesis, PPP, Glycogenesis/glycogenolysis, Krebs, ETC, selectamino acid pathways (Ala, Glu, Asp) Lipogenesis/lipolysis. Citrate/MAS/glycerol phosphate shuttlesystems, and the Cori/Glc-Ala cycles. Rules:-Draw both a mitochondrial area of metabolism and a cytoplasmic area of metabolism.-Draw the liver and its roles in glucose recycling (Cori cycle/Glc-Alanine recycling)-Avoid drawing the same molecule twice (except for separate mitochondrial/cytoplasmic populations. i.e. Design the PPP/Glycolysis so that GAP is only drawn once)-Label Carbon 4 of glucose and highlight where you would expect to find it in EVERY compound in whichit is present.-Have one or two locations for NADH/NADPH/ATP/GTP/CoQH2 – many arrows will come to/from thesespots.arrow_forward
- a. Draw the Krebs Cycle and show the entry points for the amino acids Alanine,Glutamic Acid, Asparagine, and Valine into the Krebs Cycle. (Include name of Enzymes involved) b. How many rounds of Krebs will be required to waste all Carbons of Glutamic Acid as CO2? (Show by drawing out the mechanism that occurs)arrow_forwardThe malate-aspartate shuttle allows malate to be exchanged for aspartate acrossthe inner mitochondrial membrane. (a) Describe the role of the malate-aspartate shuttle in liver cells under HIGHblood glucose conditions. Be sure to explain your answer. (b) Describe the role of the malate-aspartate shuttle in liver cells under LOW blood + glucose conditions.arrow_forward(a) Write out the net reaction, calculate ∆E ̊' for the reaction, and calculate the standard free-energy change (∆G°') for the overall oxidation/reduction reaction. (h) How many moles of ATP could theoretically be generated per mole of FADH2 oxidized by this reaction, given a ∆G ̊' of ATP synthesis of + 31 kJ/mol? How many moles of ATP could be generated per mole of FADH2 oxidized by this reaction under more typical cellular conditions (where ∆G' of ATP hydrolysis is ~ -50 kJ/mol)? Be sure to show your work and explain your answer.arrow_forward
- Indicate for the reactions below which type of enzyme and cofactor(s) (if any) would be required to catalyze each reaction shown. 1) Fru-6-P + Ery-4-P <--> GAP + Sed-7-P2) Fru-6-P + Pi <--> Fru-1,6-BP + H2O3) GTP + ADP <--> GDP + ATP4) Sed-7-P + GAP <--> Rib-5-P + Xyl-5-P5) Oxaloacetate + GTP ---> PEP + GDP + CO26) DHAP + Ery-4-P <--> Sed-1,7-BP + H2O7) Pyruvate + ATP + HCO3- ---> Oxaloacetate + ADP + Piarrow_forwardThe phosphate translocase is an inner mitochondrial membrane symporter that transports H2PO4- and H+ into the mitochondrial matrix. Phosphate is a substrate for Complex V (the ATP Synthase), the enzyme that couples the synthesis of ATP to the H+ gradient formed by the electron transport chain. (a) Bongotoxin is a hypothetical compound that inhibits the phosphate translocase of the inner mitochondrial membrane. Explain why electron transport from NADH to O2 stops when bongotoxin is added to mitochondria (i.e., why do electrons stop flowing through the electron transport chain even with an abundance of NADH and O 2 present). What effect will the addition of the weak acid dinitrophenol (DNP) to the cytosol have on electron transport in bongotoxin-inhibited mitochondria? Be sure to explain your answers. (b) How much free energy is released (in kJ) when one mole of protons flows from the mitochondrial inner membrane space (IMS) to the mitochondrial matrix when the [H+ ] in the IMS is 7.9 x…arrow_forwardWhen TMPD/ascorbate is added to mitochondria as a source of electrons (TMPD/ascorbate reduce cytochrome c directly) oxygen is reduced to H2O by the electron transport chain (ETC).(a) Approximately how many ATPs would result per O2 consumed when electrons come from TMPD/ascorbate? (b) If dinitrophenol (DNP) is added to the mitochondria in (a) above, what effect would DNP have on the yield of ATPs per O2 reduced from TMPD/ascorbate electrons?arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
BiochemistryBiochemistryISBN:9781305961135Author:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougalPublisher:Cengage Learning
Biochemistry
Biochemistry
ISBN:9781305961135
Author:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:Cengage Learning
Biomolecules - Protein - Amino acids; Author: Tutorials Point (India) Ltd.;https://www.youtube.com/watch?v=ySNVPDHJ0ek;License: Standard YouTube License, CC-BY