HeLa Cells Are a Genetic Mess HeLa cells can vary in chromosome number. Defects in proteins that orchestrate cell division result in descendant cells with too many or too few chromosomes, an outcome that is one of the ha1lmarks of cancer cells. The panel of chromosomes in FIGURE 11.9, originally published in 1989, shows all of the chromosomes in a single metaphase HeLa cell.
FIGURE 11.9 Karyotype of HeLa showing chromosomes in one cell.
Can you tell that this cell came from a female? How?
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- HeLa Cells Are a Genetic Mess HeLa cells can vary in chromosome number. Defects in proteins that orchestrate cell division result in descendant cells with too many or too few chromosomes, an outcome that is one of the ha1lmarks of cancer cells. The panel of chromosomes in FIGURE 11.9, originally published in 1989, shows all of the chromosomes in a single metaphase HeLa cell. FIGURE 11.9 Karyotype of HeLa showing chromosomes in one cell. How many extra chromosomes does this cell have, compared to a normal human body cell?arrow_forwardFigure 10.6 Which of the following is the correct order of events in mitosis? Sister chromatids line up at the metaphase plate. The kinetochore becomes attached to the mitotic spindle. The nucleus reforms and the cell divides. Cohesin proteins break down and the sister chromatids separate. The kinetochore becomes attached to the mitotic spindle. Cohesin proteins break down and the sister chromatids separate. Sister chromatids line up at the metaphase plate. The nucleus reforms and the cell divides. The kinetochore becomes attached to the cohesin proteins. Sister chromatids line up at the metaphase plate. The kinetochore breaks down and the sister chromatids separate. The nucleus reforms and the cell divides. The kinetochore becomes attached to the mitotic spindle. Sister chromatids line up at the metaphase plate. Cohesin proteins break down and the sister chromatids separate. The nucleus reforms and the cell divides.arrow_forwardFigure 6.4 Which of the following is the correct order of events in mitosis? a. Sister chromatids line up at the metaphase plate. The kinetochore becomes attached to the initotic spindle. The nucleus re-forms and the cell divides. The sister chromatids separate. b. The kinetochore becomes attached to the mitotic spindle. The sister chromatids separate. Sister chromatids line up at the metaphase plate. The nucleus re-forms and the cell divides. c. The kinetochore becomes attached to metaphase plate. Sister chromatids line up at the metaphase plate. The kinetochore breaks down and the sister chromatids separate. The nucleus re-forms and the cell divides. d. The kinetochore becomes attached to the mitotic spindle. Sister chromatids line up at the metaphase plate. The kinetochore breaks apart and the sister chromatids separate. The nucleus re-forms and the cell divides.arrow_forward
- Match the letter of the term with its description. Centriole Chromosome Chromatid Diploid DNA Gene Haploid Description makes spindle fibers is the hereditary material in chromosomes a cell containing two complete sets of chromosomes a cell containing a single set of unpaired chromosomes code for a specific trait (e.g. ability to roll the tongue) one of a pair of identical chromosomes formed by the replication of a single chromosome any of several thread-like structures, made of chromatinarrow_forwardThe figure below depicts cells from the same organism. Cell A is demonstrating which of the following: K J A Anaphase I Anaphase II O Anaphase of mitosis O Non-disjunction LLL B دے Carrow_forwardThe process of mitosis (select all that apply) Group of answer choices 1. occurs in somatic cells 2. results in diploid daughter cells 3. produces gametes 4. results in haploid daughter cells 5. produces two daughter cells 6. results in identical daughter cellsarrow_forward
- Please help me explain this thank youarrow_forwardIn dolphins, 2n=44. Drag each term or phrase to the correct position. (Each box is used once.) Somatic cell in anaphase of mitosis Ovum Somatic cell during interphase Zygote Sperm Cells with 22 chromosomes Cells with 44 chromosomes Cells with 88 chromosomesarrow_forwardA diploid organism has chromosomes. Use colours or symbols to show which chromosomes are which throughout each stage. Draw and label the chromosomes, sister chromatids, centromeres, spindle fibres, tetrad, crossing over and nucleus where appropriate. Prophase I Metaphase I Anaphase I Telophase I Prophase II Metaphase II Anaphase II Telophase II O曲T回A@ 28 Ai MacBook Pro K 2$ & 2 3 E R Y D F G K V B M command MOSISO commandarrow_forward
- The cells bellow are in the process and stages as indicated. Each cell has a 2n # of 6. In the cells below show all of the chromosomes and their proper location and draw and label the metaphase plate, kinetochore, spindle, centrosomes, homologous chromosomes, microtubules, DNA, sister chromatids, centromere MITOSIS (Metaphase) Total number of chromosomes Total number of homologous pairs of chromosomes MEIOSIS (Metaphase I)arrow_forwardThe figure below shows the number of chromosomes observed in an actively dividing cell at each stage of cell division. A B number of chromsomes per cell C 100 90 D 80 A bar graph comparing the number of chromosomes at different stages of cell division. 20 Which of the following best explains the change in the number of chromosomes between metaphase and anaphase? prophase metaphase anaphase telophase cytokinesis stage of cell division New chromosomes formed during prophase are doubled during anaphase. DNA replication occurs between metaphase and anaphase, doubling the number of chromosomes. During metaphase, a cell contains identical copies of each chromosome, and then trans- forms into sister chromatids. During anaphase, the chromatids are separated, each becoming independent chromo- somes in its respective new cellarrow_forwardMitosis is used to make more body cells while meiosis is only used to make gametes for sexual reproduction. Use the diagram to identify one similarity and one difference between mitosis and meiosis. Your answer must specifically refer to this diagram. [i.e. say what specific cells in the diagram show the similarity or difference] Mitosis Parent cell Meiosis Parent cell DNA replicates DNA replicates 2 daughter cells 2 daughter cells 4 daughter cells U.S. National Library of Medicine (Level 3) tv МacВook Air 80 DD F5 F7 F8 F9 F10 F2 F3 @ # $ & * 3 4 9. 7 8 W E R Y 一 S H J K C V M Varrow_forward
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