Concepts of Genetics (12th Edition)
Concepts of Genetics (12th Edition)
12th Edition
ISBN: 9780134604718
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
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Chapter 11, Problem 3CS
Summary Introduction

To determine: The ways the clinicians can respect the brother’s desire not to know whether he is suffering from DKC or not and can not be a suitable donor for her sister.

Introduction: Dyskeratosiscongenita (DKC) is is a rare human genetic disorder that occurs due to the mutation in the telomerase gene. DKC  disease may lead to bone marrow failure resulting in reducingthe production of blood cells and anemia.

Summary Introduction

To determine: The reason that clinicians tell the sister about her brother condition of DKC.

Introduction: A 27-year-old woman is diagnosed with a dominant form of DKC and needs a bone marrow transplant to treat the disorder. A 13-year-old brother was identified as the best immunologically matched donor for her sister

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