EBK HUMAN ANAT.+PHYSIOLOGY
11th Edition
ISBN: 9780134807362
Author: Marieb
Publisher: PEARSON CO
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Chapter 11, Problem 2CCS
Nursing Student with Neuropathic Pain
Tamara Costa broke her right tibia and has undergone two separate surgeries to repair it. Although the bone has healed, she suffers increasing pain around the incision sites. The painful area covers the lateral surface of her right leg. She can't stand wearing anything over it or even having a sheet touch it. Her diagnosis is postsurgical neuropathic pain. Pain medication has not helped.
Tamara is a second-year nursing student and has done some reading to try to understand her problem and perhaps find a solution. She has found an article that says neuropathic pain may be caused by a decreased threshold for action potential generation in pain-detecting neurons. However, she has forgotten some of her physiology and needs some help in understanding what she is reading. She has logged into the “Ask a Nurse" chat line–and she got you!
2. Tamara wants to know how a decrease in threshold in pain-detecting neurons would affect their firing. Draw a graph of an intracellular recording of a neuron showing the response to a below-threshold and an above-threshold stimulus. Then, using this graph, show how decreasing the threshold could lead to additional action potentials.
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The table below shows the results of an investigation in which the effect of
temperature and light on the yield of tomatoes in two greenhouses on a farm
was investigated.
TEMPERATURE
(°C)
AVERAGE YIELD OF TOMATOES PER
3.1
PLANT
(kg)
LOW LIGHT LEVELS
HIGH LIGHT LEVELS
5
0,5
0,5
10
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6,2
State TWO steps the investigator may have taken into
consideration during the planning stage of the investigation.
(2)
3.2
Identify the:
a) Independent variables
(2)
b) Dependent variable
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3.3
Plot a line graph showing the results of the average yield of the
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(6)
3.4
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Explain why you chose this mutation. Begin by transcribing and translating BOTH the
normal and abnormal DNA sequences. The genetic code below is for your reference.
SECOND BASE OF CODON
כ
FIRST BASE OF CODON
O
THIRD BASE OF CODON
SCAGUCAGUGAGUCAG
UUU
UUC
UCU
UAU
UGU
Phenylalanine
(F)
Tyrosine (Y)
Cysteine (C)
UCC
UAC
UGC
Serine (S)
UUA
UUG
Leucine (L)
UCA
UCG_
UAA
UGA
Stop codon
-Stop codon
UAG
UGG -Tryptophan (W)
CUU
CUC
CCU
CAU
CGU
Histidine (H)
CCC
CAC
CGC
-Leucine (L)
Proline (P)
CUA
CCA
CAA
CUG
CCG
CAG-Glutamine (Q)
-Arginine (R)
CGA
CGG
AUU
ACU
AAU
AGU
AUC
Isoleucine (1)
Asparagine (N)
ACC
AAC
Threonine (T)
AUA
ACA
AAA
Methionine (M)
Lysine (K)
AUG
ACG
Start codon
AAG
AGC-Serine (S)
-Arginine (R)
AGA
AGG
GUU
GCU
GAU
GUC
GUA
GUG
GCC
Valine (V)
-Alanine (A)
GCA
GCG
GAC
GAA
GAG
Aspartic acid
(D)
GGU
Glutamic acid
(E)
GGC
GGA
GGG
Glycine (G)
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Chapter 11 Solutions
EBK HUMAN ANAT.+PHYSIOLOGY
Ch. 11 - Prob. 1RQCh. 11 - 2. Match the names of the supporting cells found...Ch. 11 - 4. Assume that an EPSP is being generated on the...Ch. 11 - 5. The velocity of nerve impulse conduction is...Ch. 11 - 6. Chemical synapses are characterized by all of...Ch. 11 - Prob. 5RQCh. 11 - Prob. 6RQCh. 11 - 9. Inhibition of acetylcholinesterase by poisoning...Ch. 11 - 8. The anatomical region of a multipolar neuron...Ch. 11 - 11. An IPSP is inhibitory because (a) it...
Ch. 11 - 12. Identify the neuronal circuits described by...Ch. 11 - 13. Explain both the anatomical and functional...Ch. 11 - 14. (a) Describe the composition and function of...Ch. 11 - 15. (a) What is myelin? (b) How does the...Ch. 11 - 16. (a) Contrast unipolar, bipolar, and multipolar...Ch. 11 - 17. What is the polarized membrane state? How is...Ch. 11 - 18. Describe the events that must occur to...Ch. 11 - 19. Since all APs generated by a given nerve fiber...Ch. 11 - 20. (a) Explain the difference between an EPSP and...Ch. 11 - 21. Since at any moment a neuron is likely to have...Ch. 11 - Prob. 22RQCh. 11 - Prob. 13RQCh. 11 - 25. Briefly describe the three stages of neuron...Ch. 11 - 2. Local anesthetics block voltage-gated Na+...Ch. 11 - 3. When admitted to the emergency room, Sean was...Ch. 11 - 4. Rochelle developed multiple sclerosis when she...Ch. 11 - 5. In the Netherlands a young man named Jan was...Ch. 11 - Nursing Student with Neuropathic Pain Tamara Costa...Ch. 11 - Nursing Student with Neuropathic Pain Tamara Costa...Ch. 11 - Nursing Student with Neuropathic Pain
Tamara...Ch. 11 - Nursing Student with Neuropathic Pain Tamara Costa...Ch. 11 - Nursing Student with Neuropathic Pain Tamara Costa...
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