Chapter 11, Problem 22PP

Interpretation Introduction

Interpretation: The synthetic route for given transformation should be determined.

Concept Introduction:

Elimination Reaction: It is just reverse reaction of addition where substituent from the given molecule is removed via E1 (the reaction depends only on the substrate involved in the reaction) or E2 (the reaction depends on both of the substituents in the reaction) mechanism.

${\text{S}}_{\text{N}}2$Reaction: It is a nucleophilic substitution reaction in which the rate determining step depends on both of the molecules involved. The bond making and the bond breaking process happens simultaneously in this reaction. The substitution is said to be intramolecular if the reaction proceeds within the same molecule.

Hydroboration reaction: The reaction involves addition of ${\text{BH}}_{\text{3}}$ over alkene which attaches ${\text{BH}}_{\text{2}}$ to bond with less substituted position of carbon-carbon double bonds and $\text{H}$ to more substituted position of carbon-carbon double bonds in order to achieve the product with less substitution.

Leaving group: it is a fragment that leaves substrate with a pair of electrons via heterolytic bond cleavage.

Nucleophile: donates pair of electrons to positively charged substrate resulting in the formation of chemical bond.

Ozonolysis Reaction: It is an oxidative reaction which is used to oxidise the carbon-carbon double and triple bond.

Oxidation Reaction: It involves loss of electrons, addition of oxygen atoms or removal of hydrogen atoms.

Reduction Reaction: It is just opposite of oxidation reaction which involves removal of oxygen atoms or addition of hydrogen atoms and addition of electrons.