EBK BIOLOGY
5th Edition
ISBN: 9780133954425
Author: Maier
Publisher: YUZU
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Chapter 11, Problem 1LTB
Summary Introduction
To write:
The types of drugs which have helped to reduce the death rate due to tuberculosis and the reason they have become less effective.
Introduction:
Tuberculosis is caused by the bacteria Mycobacterium Tuberculosis which affects the lungs. Antibiotics are the drugs that kill microbes including the bacteria. Antibiotics are effective in controlling infections through the immune system.
Expert Solution & Answer
Explanation of Solution
The discovery of antibiotics which are drugs killing the microbes including bacteria revolutionized the treatment of tuberculosis. After scientists began using drugs for tuberculosis, some individuals became ill again after successful treatment. The two characteristics of early treatment strategies for tuberculosis that developed drug resistance were using drugs for a short duration and a single type of antibiotic at a time for the treatment of tuberculosis patients.
In order to determine drug resistance, it is required to maintain the drug therapy for months until the signs of bacterial infections are clear, and usage of combination drug therapy i.e., use of multiple drugs on active infections to avoid the selection of variants which already exist in the population.
Conclusion
Thus, discovery of the antibiotics revolutionized the treatment of tuberculosis. The two characteristics of early treatment strategies for tuberculosis that developed drug resistance were using drugs for a short duration and a single type of antibiotic at a time for treatment of tuberculosis patients.
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