
Concept explainers
(a)
Interpretation:
The curved-arrow mechanism for nucleophilic substitution reaction of mechlorethamine with water is to be stated.
Concept introduction:
Nucleophilic substitution reactions are the reactions in which an nucleophile attacks the compounds and substitute a group which also acts as a nucleophile. The NGP is a phenomenon which helps in the enhancement of the rate of nucleophilic substitution reaction.
(b)
Interpretation:
The curved-arrow mechanism for cross-linking of the DNA molecule by mechlorethamine is to be stated.
Concept introduction:
Nucleophilic substitution reactions are the reactions in which an nucleophile attacks the compounds and substitute a group which also acts as a nucleophile. The NGP is a phenomenon which helps in the enhancement of the rate of nucleophilic substitution reaction.

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