Campbell Biology: Concepts & Connections (8th Edition)
Campbell Biology: Concepts & Connections (8th Edition)
8th Edition
ISBN: 9780321885326
Author: Jane B. Reece, Martha R. Taylor, Eric J. Simon, Jean L. Dickey, Kelly A. Hogan
Publisher: PEARSON
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Chapter 11, Problem 10TYK

A mutation in a single gene may cause a major change in the body of a fruit fly, such as an extra pair of legs or wings. Yet it probably takes the combined action of hundreds or thousands of genes to produce a wing or leg. How can a change in just one gene cause such a big change in the body?

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One unexpected result of the sequencing of the human genome was the finding that mutations in a single gene can be responsible for multiple distinct disorders. How do you think mutations in a single gene can have such diverse effects?
Synpolydactyly is an abnormality characterized by webbing between partially or completely duplicated fingers or toes (Figure 18.15). The same mutations that cause the human phenotype give rise to a similar phenotype in mice. In what family of genes do you think these mutations occur?
You are working in a lab that studies stickleback fish. These fish normally have three spines that occur on the back of the stickleback. One day you notice that a young stickleback has no spines on its back but instead has three spines growing out of the top of its head! (answer both questions) question 1: A mutation in what type of gene is probably the cause of this unusual situation? Why? question #2: would you expect the proteins that make the spines to be different in the mutant fish compared to a wildtype fish. Why or why not?
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