Human Biology
16th Edition
ISBN: 9781260482799
Author: Mader, Sylvia
Publisher: MCGRAW-HILL HIGHER EDUCATION
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Chapter 10.5, Problem 2CYP
Summary Introduction
To analyze:
The importance of the respiratory control center in the brain.
Introduction:
A respiratory system is a group of an organ that include air passages, lungs, pulmonary vessels and breathing muscles that help in exchange of gases between air and blood. The gaseous exchange also takes place between the blood and billions of body cells. Each organ of the respiratory system helps in air distribution, but alveoli are responsible for actual gaseous exchange.
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Biopharmaceutics and Pharmacokinetics:Two-Compartment Model Instant Absorption Questions
SHOW ALL WORK, including equation used, variables used and each step to your solution, report your regression lines and axes names (with units if appropriate) :Calculate a-q
a) B1,
b) B2,
c) hybrid rate constant (1)
d) hybrid rate constant (2)
e) t1/2,dist
f) t1/2,elim
g) k10
h) k12
i) k21
j) initial concentration (C0)
k) central compartment volume (V1)
l) steady-state volume (Vss)
m) clearance (CL) AUC (0→10 min) using trapezoidal rule
n) AUC (20→30 min) using trapezoidal rule
o) AUCtail (AUC360→∞)
p) total AUC (using short cut method)
q) volume from AUC (VAUC)
Glitazones reduce insulin resistance by binding to a transcription factor in adipocytes, thereby reducing thesecretion of fatty acids. Glitazones are taken orally (in pill form). Using pharmacokinetic modeling, deriveequations to describe how the concentration of glitazones varies in the plasma as a function of time. Yourequations should be of the form: dCglitazone /dt = something, or dMglitazone /dt = something. Your model shouldinclude three compartments: the gut, the plasma, and the fatty tissues. Make sure to include a diagram thatillustrates your thinking, state all assumptions, and define your variables. Do not solve the equations.
Chapter 10 Solutions
Human Biology
Ch. 10.1 - Prob. 1LOCh. 10.1 - Prob. 2LOCh. 10.1 - Prob. 3LOCh. 10.1 - Trace the path of air from the nasal cavities to...Ch. 10.1 - Prob. 2CYPCh. 10.1 - Prob. 3CYPCh. 10.2 - Prob. 1LOCh. 10.2 - Prob. 2LOCh. 10.2 - Prob. 3LOCh. 10.2 - Prob. 1CYP
Ch. 10.2 - Prob. 2CYPCh. 10.2 - Prob. 3CYPCh. 10.3 - Prob. 1LOCh. 10.3 - Prob. 2LOCh. 10.3 - Explain how the alveoli increase the efficiency of...Ch. 10.3 - Prob. 1CYPCh. 10.3 - Prob. 2CYPCh. 10.3 - Prob. 3CYPCh. 10.3 - Prob. 1BTSCh. 10.3 - Prob. 2BTSCh. 10.4 - Prob. 1LOCh. 10.4 - Prob. 2LOCh. 10.4 - Prob. 3LOCh. 10.4 - Prob. 1CYPCh. 10.4 - Prob. 2CYPCh. 10.4 - Discuss what effect insufficient expiration might...Ch. 10.5 - Prob. 1LOCh. 10.5 - Prob. 2LOCh. 10.5 - Prob. 1CYPCh. 10.5 - Prob. 2CYPCh. 10.5 - Prob. 3CYPCh. 10.6 - Prob. 1LOCh. 10.6 - Prob. 2LOCh. 10.6 - Prob. 3LOCh. 10.6 - Prob. 1CYPCh. 10.6 - Prob. 2CYPCh. 10.6 - Detail the influence of PO2Â on both external and...Ch. 10.7 - Prob. 1LOCh. 10.7 - Prob. 2LOCh. 10.7 - Prob. 3LOCh. 10.7 - Prob. 1.1BTHCh. 10.7 - Prob. 1.2BTHCh. 10.7 - Prob. 2.1BTHCh. 10.7 - Prob. 2.2BTHCh. 10.7 - Prob. 1CYPCh. 10.7 - Prob. 2CYPCh. 10.7 - Prob. 3CYPCh. 10 - Prob. 1ACh. 10 - Prob. 2ACh. 10 - Prob. 3ACh. 10 - Prob. 4ACh. 10 - Prob. 5ACh. 10 - Prob. 6ACh. 10 - Prob. 7ACh. 10 - Prob. 8ACh. 10 - Prob. 9ACh. 10 - Prob. 10ACh. 10 - Prob. 11ACh. 10 - Prob. 12ACh. 10 - Prob. 13ACh. 10 - Prob. 14ACh. 10 - Prob. 15ACh. 10 - 1. Children may also suffer from obstructive sleep...Ch. 10 - Explain the expression “The food went down the...Ch. 10 - Prob. 3TCCh. 10 - Prob. 4TCCh. 10 - Prob. 5TC
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