Statistics: The Art and Science of Learning from Data (4th Edition)
Statistics: The Art and Science of Learning from Data (4th Edition)
4th Edition
ISBN: 9780321997838
Author: Alan Agresti, Christine A. Franklin, Bernhard Klingenberg
Publisher: PEARSON
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Chapter 10.2, Problem 22PB

Chelation useless? Chelation is an alternative therapy for heart disease that uses repeated intravenous administration of a human-made amino acid in combination with oral vitamins and minerals. Practitioners believe it removes calcium deposits from buildup in arteries. However, the evidence for a positive effect is anecdotal or comes from nonrandomized, uncontrolled studies. A double-blind randomized clinical trial comparing chelation to placebo used a treadmill test in which the response was the length of time until a subject experienced ischemia (lack of blood flow and oxygen to the heart muscle).

After 27 weeks of treatment, the sample mean time for the chelation group was 652 seconds. A 95% confidence interval for the population mean for chelation minus the population mean for placebo was −53 to 36 seconds. Explain how to interpret the confidence interval.

  1. a. A significance test comparing the means had P-value = 0.69. Specify the hypotheses for this test, which was two-sided.
  2. b. The authors concluded from the test, “There is no evidence to support a beneficial effect of chelation therapy” (M. Knudtson et al., JAMA, vol. 287, p. 481, 2002). Explain how this conclusion agrees with inference based on the values in the confidence interval.
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Chapter 10 Solutions

Statistics: The Art and Science of Learning from Data (4th Edition)

Ch. 10.1 - Hormone therapy for menopause The Womens Health...Ch. 10.1 - Obama A/B testing To increase Barack Obamas...Ch. 10.1 - Believe in heaven and hell A recent survey asked...Ch. 10.2 - Alcohol and Energy Drinks A 2013 article in the...Ch. 10.2 - Address global warming You would like to determine...Ch. 10.2 - Housework for women and men Do women tend to spend...Ch. 10.2 - More confident about housework Refer to part c in...Ch. 10.2 - Employment by gender The study described in...Ch. 10.2 - Ideal number of children In 2014, the GSS asked,...Ch. 10.2 - Pay by gender The study described in the Exercise...Ch. 10.2 - Bulimia CI A study of bulimia among college women...Ch. 10.2 - Chelation useless? Chelation is an alternative...Ch. 10.2 - Nicotine dependence A study on nicotine dependence...Ch. 10.2 - Inhaling affect HONC? Refer to the previous...Ch. 10.2 - Females or males more nicotine dependent? Refer to...Ch. 10.2 - Female and male monthly smokers Refer to the...Ch. 10.2 - Body language In an experiment investigating body...Ch. 10.2 - Student survey Refer to the FL Student Survey data...Ch. 10.2 - Study time A graduate teaching assistant for...Ch. 10.2 - More on study time Refer to the data in the...Ch. 10.2 - Time spent on social networks As part of a class...Ch. 10.2 - More time on social networks In the previous...Ch. 10.2 - Normal assumption The methods of this section make...Ch. 10.2 - Vital capacity One of the authors of this book has...Ch. 10.3 - Body dissatisfaction Female college student...Ch. 10.3 - Body dissatisfaction test Refer to the previous...Ch. 10.3 - Surgery versus placebo for knee pain Refer to...Ch. 10.3 - Comparing clinical therapies A clinical...Ch. 10.3 - Clinical therapies 2 Refer to the previous...Ch. 10.3 - Vegetarians more liberal? When a sample of social...Ch. 10.3 - Teeth whitening results One scientific test of...Ch. 10.3 - Permuting therapies Refer to Exercise 10.38, which...Ch. 10.3 - Permutations equally likely Refer to the previous...Ch. 10.3 - Two-sided permutation P-value Refer to the...Ch. 10.3 - Time spent on social networks revisited Exercise...Ch. 10.3 - Compare permutation test to t test Refer to the...Ch. 10.3 - Dominance of politicians For a rating experiment,...Ch. 10.3 - Sampling distribution of x1x2 Refer to Example 12,...Ch. 10.4 - Does exercise help blood pressure? Several recent...Ch. 10.4 - Test for blood pressure Refer to the previous...Ch. 10.4 - Social activities for students As part of her...Ch. 10.4 - More social activities Refer to the previous...Ch. 10.4 - Movies versus parties Refer to the previous two...Ch. 10.4 - Freshman 15 a myth? The freshman 15 is the name of...Ch. 10.4 - Checking for freshman 15 Refer to the previous...Ch. 10.4 - Internet book prices Annas project for her...Ch. 10.4 - Comparing hook prices 2 For the data in the...Ch. 10.4 - Lung capacity revisited Refer to Exercise 10.34...Ch. 10.4 - Comparing speech recognition systems Table 1020 in...Ch. 10.4 - Treat juveniles as adults? The table that follows...Ch. 10.4 - Change coffee brand? A study was conducted to see...Ch. 10.4 - Presidents popularity Last month a random sample...Ch. 10.4 - Heaven and hell Results of polls about belief in...Ch. 10.4 - Heaven and hell around the world Refer to the...Ch. 10.5 - Prob. 65PBCh. 10.5 - Prob. 66PBCh. 10.5 - Basketball paradox The following list summarizes...Ch. 10.5 - Prob. 68PBCh. 10.5 - Prob. 69PBCh. 10.5 - Prob. 70PBCh. 10.5 - Breast cancer over time The percentage of women...Ch. 10 - Pick the method Steve Solomon, the owner of...Ch. 10 - Prob. 73CPCh. 10 - BMI then and now The Centers for Disease Control...Ch. 10 - Marijuana and gender In a survey conducted by...Ch. 10 - Prob. 76CPCh. 10 - Belief depend on gender? Refer to the previous...Ch. 10 - Prob. 78CPCh. 10 - Prob. 79CPCh. 10 - Prob. 80CPCh. 10 - Prob. 81CPCh. 10 - Prob. 82CPCh. 10 - Prob. 83CPCh. 10 - Prob. 84CPCh. 10 - Prob. 85CPCh. 10 - How often do you feel sad? A recent General Social...Ch. 10 - Prob. 87CPCh. 10 - Prob. 88CPCh. 10 - Prob. 89CPCh. 10 - Equal pay in sports? The following data refer to a...Ch. 10 - Prob. 91CPCh. 10 - Prob. 92CPCh. 10 - Anorexia again Refer to Exercise 10.89, comparing...Ch. 10 - Breast-feeding helps IQ? A Danish study of...Ch. 10 - Prob. 95CPCh. 10 - Prob. 96CPCh. 10 - Prob. 97CPCh. 10 - Prob. 98CPCh. 10 - Prob. 99CPCh. 10 - Prob. 100CPCh. 10 - Prob. 101CPCh. 10 - Prob. 102CPCh. 10 - Prob. 103CPCh. 10 - Prob. 104CPCh. 10 - Belief in ghosts and in astrology A poll by Louis...Ch. 10 - Death penalty paradox Exercise 3.58 showed results...Ch. 10 - Prob. 107CPCh. 10 - Prob. 108CPCh. 10 - Prob. 109CPCh. 10 - Prob. 111CPCh. 10 - Pay discrimination against women? A Time Magazine...Ch. 10 - Mean of permutation distribution Refer to Example...Ch. 10 - Treating math anxiety Two new programs were...Ch. 10 - Prob. 115CPCh. 10 - Prob. 116CPCh. 10 - Prob. 117CPCh. 10 - Multiple choice: Sample size and significance If...Ch. 10 - Prob. 119CPCh. 10 - Prob. 120CPCh. 10 - Prob. 121CPCh. 10 - Prob. 122CPCh. 10 - Prob. 123CPCh. 10 - Prob. 124CPCh. 10 - Prob. 125CPCh. 10 - Prob. 126CPCh. 10 - Null standard error for matched pairs Under the...Ch. 10 - Prob. 128CP
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