Organic Chemistry
Organic Chemistry
2nd Edition
ISBN: 9781118452288
Author: David R. Klein
Publisher: WILEY
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Chapter 10, Problem 62IP
Interpretation Introduction

Interpretation:

The synthetic route for the preparation of given transformation (mechanism) should be determined.

Concept Introduction:

Soda amide: The strong base of NaNH2/NH3 will deprotonate alkynes, alcohols and other organic functional groups with acidic protons such as asters and ketones. It is also a very strong nucleophile. It is a strong base and excellent nucleophile. It’s used deprotonated of weak acids and also for elimination reaction.

Acid-Base Reaction: This type of chemical process typified by the exchange of one or more hydrogens ions H+, between species that may be neutral molecules or electrically charged ions.

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Organic Chemistry

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