ANATOMY AND PHYSIOLOGY
ANATOMY AND PHYSIOLOGY
17th Edition
ISBN: 9781630180928
Author: OpenStax
Publisher: OPENSTAX C
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Chapter 10, Problem 47CTQ

Describe the differences between single-unit smooth muscle and multiunit smooth muscle.

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1. In vivo testing provides valuable insight into a drug’s kinetics. Assessing drug kinetics following multiple different routes of administration provides greater insight than just a single route of administration alone. The following data was collected in 250 g rats following bolus iv, oral (po), and intraperitoneal (ip) administration.Using this data and set of graphs, determine: (a) k, C0, V, and AUC* for the bolus iv data  (b) k, ka, B1, and AUC* for the po data  (c) k, ka, B1, and AUC* for the ip data  (d) relative bioavailability for po vs ip, Fpo/Fip  (e) absolute po bioavailability, (f)Fpo absolute ip bioavailability, Fip    MAKE SURE ANSWERS HAVE UNITS if appropriate. SHOW ALL WORK, including equation used, variables used and each step to your solution.
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Chapter 10 Solutions

ANATOMY AND PHYSIOLOGY

Ch. 10 - The cell membrane of a muscle fiber is called...Ch. 10 - Muscle relaxation occurs when ________. calcium...Ch. 10 - During muscle contraction, the cross-bridge...Ch. 10 - Thin and thick filaments are organized into...Ch. 10 - During which phase of a twitch in a muscle fiber...Ch. 10 - Muscle fatigue is caused by ________. buildup of...Ch. 10 - A sprinter would experience muscle fatigue sooner...Ch. 10 - What aspect of creatine phosphate allows it to...Ch. 10 - Dmg X blocks ATP regeneration from ADP and...Ch. 10 - The muscles of a professional sprinter are most...Ch. 10 - The muscles of a professional marathon runner are...Ch. 10 - Which of the following statements is true? Fast...Ch. 10 - Which of the following statements is false? Slow...Ch. 10 - Cardiac muscles differ from skeletal muscles in...Ch. 10 - If cardiac muscle cells were prevented from...Ch. 10 - Smooth muscles differ from skeletal and cardiac...Ch. 10 - Which of the following statements describes smooth...Ch. 10 - From which embryonic cell type does muscle tissue...Ch. 10 - Which cell type helps to repair injured muscle...Ch. 10 - Why is elasticity an important quality of muscle...Ch. 10 - What would happen to skeletal muscle if the...Ch. 10 - Describe how tendons facilitate body movement.Ch. 10 - What are the five primary functions of skeletal...Ch. 10 - What are the opposite roles of voltage-gated...Ch. 10 - How would muscle contractions be affected if...Ch. 10 - What causes the striated appearance of skeletal...Ch. 10 - How would muscle contractions be affected if ATP...Ch. 10 - Why does a motor unit of the eye have few muscle...Ch. 10 - What factors contribute to the amount of tension...Ch. 10 - Why do muscle cells use creatine phosphate instead...Ch. 10 - Is aerobic respiration more or less efficient than...Ch. 10 - What changes occur at the cellular level in...Ch. 10 - What changes occur at the cellular level in...Ch. 10 - What would be the drawback of cardiac contractions...Ch. 10 - How are cardiac muscle cells similar to and...Ch. 10 - Why can smooth muscles conn act over a wider range...Ch. 10 - Describe the differences between single-unit...Ch. 10 - Why is muscle that has sustained significant...Ch. 10 - Which muscle type(s) (skeletal, smooth, or...
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