Principles of Anatomy and Physiology
15th Edition
ISBN: 9781119329398
Author: Gerard J Tortora, Bryan Derrickson
Publisher: John Wiley & Sons Inc
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Chapter 10, Problem 3CTQ
Polio is a disease caused by a virus that can attack the somatic motor neurons in the central nervous system. Individuals who suffer from polio can develop muscle weakness and atrophy. In a certain percentage of cases, the individuals may die due to respiratory paralysis. Relate your knowledge of how muscle fibers function to the symptoms exhibited by infected individuals.
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Tetanus is a disease caused by Clostridium tetani characterized by muscle spasms. Just like the toxin produced by Clostridium botulinum, this toxin produced by C. tetani interferes with muscle contractions. Where botulina toxin causes paralysis, C. tetani toxin causes muscle spasms and painful contractions lasting minutes at a time. Additional symptoms include stiffness and rigidity of muscles. Using your knowledge of how muscles contract explain what steps within a muscle contraction are being interfered with to cause these symptoms?
Necrotizing fasciitis is a serious bacterial infection. Necrosis is the death of tissues in the body. Considering the organization of the connective tissue sheaths of skeletal muscle, explain how this infection could spread rapidly throughout the body.
Which of the following step(s) about the excitation of skeletal muscle is/are incorrect?
1. Acetylcholine is released and binds to motor end plate receptors
2. An action potential is created and moves down T-tubules
3. Calcium is released from the sarcoplasmic reticulum
4. Calcium ions bind to tropomyosin to shift troponin off the binding sites for cross-bridging
5. Myosin forms cross-bridges and binds with actin to pull it towards middle of sarcomere
Chapter 10 Solutions
Principles of Anatomy and Physiology
Ch. 10 - To determine:
l. What features distinguish the...Ch. 10 - List the general functions of muscular tissue.Ch. 10 - 3. Describe the four properties of muscular...Ch. 10 - What types of fascia cover skeletal muscles?Ch. 10 - Why is a rich blood supply important for muscle...Ch. 10 - How are the structures of thin and thick filaments...Ch. 10 - What roles do contractile, regulatory, and...Ch. 10 - Prob. 8CPCh. 10 - To determined
9. How does sareomere length...Ch. 10 - Prob. 10CP
Ch. 10 - Which ATP-producing reactions are aerobic and...Ch. 10 - To determine:
12. Which sources provide ATP during...Ch. 10 - Prob. 13CPCh. 10 - Why is the term recovery oxygen uptake more...Ch. 10 - Prob. 15CPCh. 10 - What is motor unit recruitment?Ch. 10 - Prob. 17CPCh. 10 - Prob. 18CPCh. 10 - Prob. 19CPCh. 10 - Prob. 20CPCh. 10 - Prob. 21CPCh. 10 - On a cellular level, what causes muscle...Ch. 10 - What are the similarities among and differences...Ch. 10 - 24. What are the differences between visceral and...Ch. 10 - How are skeletal and smooth muscle similar? How do...Ch. 10 - 26. Which type of muscular tissue has the highest...Ch. 10 - Q. Which structures develop from myotomes,...Ch. 10 - Prob. 28CPCh. 10 - 29. Why do you think a healthy 30-year-old can...Ch. 10 - l. Weightlifter Jamal has been practicing many...Ch. 10 - Prob. 2CTQCh. 10 - Polio is a disease caused by a virus that can...
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- Which statement or statements describe why depletion of ATP after death leads to rigor mortis? Select all that apply. ATP is required to move tropomyosin back over the active sites of thin filaments. ATP is required for myosin thick filaments to detach from actin thin filaments. ATP is required to pump calcium back into the sarcoplasmic reticulum. ATP is required for the action potential to spread across the sarcolemma.arrow_forwardCharacteristics of smooth muscles fibers are: spindle shaped, unbranched, unstriated, uninucleate and involuntary spindle shaped, unbranched, multistriated, uninucleate and involuntary cylinderical, unbranched, unstriated, uninucleate and involuntary Cylindrical, unbranched, striated, multinucleate and involuntary Fat cells are characterized by: affected by starvation present in adults they are heat insulator they have signet ring appearance abundant mitochondriaarrow_forwardWhich of the following sentences is NOT correct? A. White fibers make up fast-twitch muscle B. Muscle spindle is a type of receptor that detects muscle length C. Exocrine gland secretes its product directly into the bloodstream D. When an action potential is generated within a motor neuron, every muscle cell of the motor unit is stimulated to contractarrow_forward
- Which statement or statements describe the role of calcium in the stimulation of muscle fibers? Select all that apply. When the action potential reaches the axon terminals of a neuron, calcium channels open and calcium floods into the axon terminal, triggering the release of synaptic vesicles. When calcium ions flood out of the sarcoplasmic reticulum, they bind troponin molecules and troponin removes tropomyosin from the active sites on thin filaments. When myosin thick filaments are walking along actin thin filaments (the cross bridge cycle), calcium ions must be available to bind to myosin so that it can let go of the thin filaments and take another "step". When synaptic vesicles fuse with the plasma membrane of axon terminals, calcium is released into the synaptic cleft and binds to receptors in the motor end plate.arrow_forwardA motor unit associated with the stimulation of skeletal muscle is designated as a 1:8 motor unit. Which of the following statements is correct? The motor unit consists of one somatic neuron and 8 myofibers (muscle fibers) Each of the myofibers in the motor unit is innervated by more than one neuron It is part of the autonomic nervous system The neuron in the motor unit is an afferent neuronarrow_forwardOne of the primary characteristics of all muscle tissue is contractility, the ability to shorten (contract) and lengthen (relax). You've identified the various components of a myofibril above. Now, use the table below to indicate what occurs to each band, line, or zone when the muscle contracts vs. relaxes. What occurs to this region / structure during contraction/relaxation? Region / Structure A-Band H-Band I-Band M-Line Z-Line Zone of Overlap Sarcomere No change Shortens Lengthens Muscle Contraction Muscle Relaxationarrow_forward
- Calmodulin is found in smooth muscle cells and performs a similar function to troponin in striated muscle fibers. However, calmodulin not only gets activated by Ca2+ but also slows the release of Ca2+ from the sarcoplasmic reticulum. How might this difference relate to the different kinds of contractions smooth muscles do in comparison to striated muscles?arrow_forwardWhich of the following are aspects of the structure of skeletal muscle? Select all that apply. The muscle fibers are parallel to one another and have a striated appearance. They have more mitochondria than other types of muscle cells. Each fiber contains many units of contraction and protein filaments. Cells are branched or unbranched with single nuclei. It consists of cylindrical cells called muscle fibers that have multiple nuclei.arrow_forwardWith muscular dystrophy, the membrane of muscle cells is destroyed. Given how muscle cells contract, which of the following would fail to happen? Reuptake of acetylcholine by the muscle cells ) Reuptake of acetylcholine by lower motor neurons ) Action potential conduction on muscle cells Action potential conduction on the lower motor neuronsarrow_forward
- From the following choices, choose the THREE, that would result in prevention of muscle contraction (in other words, which three descriptive changes below would result in flaccid paralysis of a muscle). exocytosis of acetylcholine is constant, even without action potential injection of botulinum toxin calcium cannot be pumped back into the terminal cisternae acetylcholine receptor remains open to sodium active sites on actin a permanently exposed dramatically increase the activity of acetylcholinesterase calcium cannot bind troponinarrow_forwardDistinguish between skeletal, smooth, and cardiac muscle in terms of location and whether they have sarcomeres. Use the sliding filament model to draw how thin filaments, thick filaments, and Z lines move during muscle contraction. Predict how perturbations of acetylcholine release, reception, or breakdown will influence muscle contraction. Predict how perturbations of actin, troponin, tropomyosin, myosin, or calcium would influence muscle contraction. Distinguish between the sympathetic and parasympathetic nervous system. Predict how changes in stress levels or situations would affect activation of the sympathetic and parasympathetic nervous system, levels of epinephrine and norepinephrine, and blood pressure.arrow_forwardIn order to study and understand muscle diseases, one needs to have a good understanding of normal muscle function. Briefly outline the process of cross-bridge cycling in muscle contraction. Be sure to highlight the role of Ca2+ and ATP/ADP in the process.arrow_forward
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