BIOCHEMISTRY
BIOCHEMISTRY
9th Edition
ISBN: 2818440090622
Author: BERG
Publisher: MAC HIGHER
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Chapter 10, Problem 36P
Interpretation Introduction

Interpretation:

A reason for the regularity in the heptapeptide units containing hydrophobic residues, a and d, possessed by the three types of the fibrin chains is to be stated.

Concept introduction:

Proteins are the biomolecules which are composed of the long chain of amino acid residues. A type of non-globular protein which is fibrous and participates in the clotting of blood is known as fibrin.

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The carbon-nitrogen peptide bond is rigid, but rotation can take place about the bond between the nitrogen and α-carbon atoms and the bond between the α-carbon and the carbonyl carbon atom. These bond angles define the conformation of the peptide chain. Consider the Ramachandran plot shown to answer both questions. (degrees) 180 120 60 60 0 Which observation most likely describes part of an observed a helix? p=-59 degrees; = +150 degrees; many Ser residues cp-140 degrees; w = +130 degrees; many Val residues op-57 degrees; w = -47 degrees; many Pro residues op-60 degrees; y = -47 degrees; many Ala residues p = +60 degrees; y = +40 degrees; many Gly residues -60 -120 -180 -180 0 ➜ (degrees) 180
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