Pearson eText Bauman Microbiology with Diseases by Body Systems -- Instant Access (Pearson+)
5th Edition
ISBN: 9780135891018
Author: ROBERT BAUMAN
Publisher: PEARSON+
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Textbook Question
Chapter 10, Problem 2TMW
Some antimicrobial drugs are harmful to humans. Why can physicians use such drugs despite the potential danger?
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Which of the following types of antimicrobial drugs make microbes more susceptible
to osmotic pressure?
1) drugs that inhibit nucleic acid synthesis
O 2) drugs that inhibit metabolic pathways
3) drugs that inhibit cell wall synthesis
4) drugs that block a pathogen's recognition of its host
5) drugs that inhibit protein synthesis
The type of antimicrobial drug that would be most likely to have toxic effects in
humans based on the premise of selective toxicity when treating microbial infection
would be a drug that
O 1) inhibits the synthesis of the cell wall
O 2) inhibits metabolic pathways
O 3) disrupts the cytoplasmic membrane
4) inhibits protein synthesis
5) All of the above have equal potential to be toxic
1) It is sometimes best to use two different antibiotics in order to treat an infection. This might happen because of the :
-Symbiotic effects of the drugs
-Synergistic effects of the drugs
-Antagonistic effects of the two drugs
2) What was the first synthetic antimicrobial?
- Salvarsan
- Tetracycline
- Sulfonimide
Chapter 10 Solutions
Pearson eText Bauman Microbiology with Diseases by Body Systems -- Instant Access (Pearson+)
Ch. 10 - Prob. 1TMWCh. 10 - Some antimicrobial drugs are harmful to humans....Ch. 10 - Antibiotic Overkill A young woman was taking...Ch. 10 - Prob. 2CCSCh. 10 - Prob. 3TMWCh. 10 - Why is it incorrect to say that an individual...Ch. 10 - Prob. 1EDCSCh. 10 - Prob. 3CCSCh. 10 - Prob. 1MCCh. 10 - In a Kirby-Bauer susceptibility test, the presence...
Ch. 10 - Prob. 3MCCh. 10 - Prob. 4MCCh. 10 - Cross resistance is _____. a. the deactivation of...Ch. 10 - Prob. 6MCCh. 10 - Prob. 7MCCh. 10 - Prob. 8MCCh. 10 - Prob. 9MCCh. 10 - Prob. 10MCCh. 10 - Label each figure below to indicate the class of...Ch. 10 - What specific test for antimicrobial efficacy is...Ch. 10 - What characteristics would an ideal...Ch. 10 - Prob. 2SACh. 10 - Why is the fact that drug Z destroys the NAM...Ch. 10 - Given that both human cells and pathogens...Ch. 10 - Prob. 5SACh. 10 - Prob. 6SACh. 10 - Prob. 7SACh. 10 - Prob. 8SACh. 10 - Compare and contrast the actions of polyenes,...Ch. 10 - Prob. 10SACh. 10 - Prob. 1CTCh. 10 - How does Penicillium escape the effects of the...Ch. 10 - How might a colony of Bacillus licheniformis...Ch. 10 - Fewer than 1 % of known antibiotics have any...Ch. 10 - In an issue of News of the Lepidopterists Society,...Ch. 10 - Even though aminoglycosides such as gentamicin can...Ch. 10 - Prob. 7CTCh. 10 - Prob. 8CTCh. 10 - Why might amphotericin B affect the kidneys more...Ch. 10 - Antiparasitic drugs in the benzimidazole family...Ch. 10 - Prob. 11CTCh. 10 - Scientists have cultured bacteria isolated from...Ch. 10 - Prob. 13CTCh. 10 - Prob. 14CTCh. 10 - Enterococcus faecium is frequently resistant to...Ch. 10 - Prob. 1CM
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- Broad-spectrum drugs target a wide variety of bacterial pathogens. Even when the broad-spectrum drug is capable of killing a target pathogen, it may not be the best treatment. Which statement best explains why a broad spectrum drug might be an undesirable treatment choice? Broad-spectrum antimicrobials are usually toxic to the host cells. Broad-spectrum antimicrobials only work if they are used shortly after the infection begins. Broad-spectrum antimicrobials may kill much of the normal microbiota. Broad-spectrum antimicrobials are not able to kill bacteria that are in their log phase of growth. Broad-spectrum antimicrobials may stimulate excess growth of the normal microbiota.arrow_forwardA broad- spectrum antimicrobial drug would be a drug that attacks many different microbial sites. True or false.arrow_forwardWhich of the following is true of selective toxicity? O 1) It refers to the process of determining the correct dose of a particular drug O 2) To be effective, an antimicrobial agent must be more toxic to the patient than 2) the pathogen O 3) It contributes to antibiotic resistance O 4) It refers to the body's ability to protect the brain and eye 5) It takes advantage of metabolic and structural differences between host and pathogenarrow_forward
- See picture-- match microbial drug to its action. There can be more than one action per drug.arrow_forwardlist 4 families of antimicrobials that belong to the beta-lactam grouparrow_forwardMany antimicrobials were discovered in the first half of the 20th century. Match the early antimicrobial drugs with their description and/or target disease: salvarsan sulfanilamide penicillin prontosil Choices - first synthetic antimicrobial synthetic dye used to treat streptococcal and staphylococcal infections treatment for syphilis first discovered natural antibioticarrow_forward
- Many antibiotics used in modern medicine are compounds made by fungi that inhibit bacterial protein synthesis. Describe the specific effect of the following antimicrobial drugs: (i) Tetracycline (ii) Puromycin (iii) Alpha-Amanitinarrow_forwardImportant characteristics of antimicrobial drugs include: a) readily delivered to the site of infection b) high toxicity against microbial cells c) do not cause serious side effects in humans d) remains active in body tissues and fluids e) all of the abovearrow_forwardWhich antimicrobial agents have the narrowest spectrum of action? antivirals antifungals beta-lactams sulfanilamidesBottom of Form Penicillin is a narrow spectrum antibiotic because it only affects bacteria with mycolic acid in its cell wall, such as Mycobacterium tuberculosis. it only affects viruses it only affects Gram-negative organisms it only affects Gram-positive organismsBottom of Form Which of the following antibiotics might be destroyed by beta-lactamase enzymes? amphotericin B and ciprofloxacin streptomycin penicillin ciprofloxacinBottom of Form Which is incorrect about how the pharmaceutical industry has discovered drugs over the past 100 years? The process of discovery has involved custom-designing chemical compounds that we know will bind to target enzymes. The process of discovery has involved screening for chemicals that are toxic to bacteria while being less toxic to human cells. The process of discovery has involved screening thousands of randomly…arrow_forward
- List 10 characteristics of an ideal antimicrobial drug.arrow_forwardSoap and detergents are categorized as which type of antimicrobial chemical? oxidizing agent aldehyde surfactant alcoholarrow_forwardWhich of the following is not a factor that should be considered when selecting a antimicrobial drug? A. The nature of the microbe causing the infection B. The overall medical condition of the patient C. The origin of the drug D. The degree of susceptibility of the microbe to that drugarrow_forward
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