Essentials of Human Anatomy & Physiology Laboratory Manual (7th Edition)
Essentials of Human Anatomy & Physiology Laboratory Manual (7th Edition)
7th Edition
ISBN: 9780134424835
Author: Elaine N. Marieb, Pamela B. Jackson
Publisher: PEARSON
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Chapter 10, Problem 25SAE
Summary Introduction

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When an Rhesus-negative (Rh-) person receives blood from an Rhesus-positive (Rh+) person, the reason behind the person to have transfusion reaction in the second blood transfusion and not during the first transfusion reaction..

Introduction:

The Rh blood group contains the Rh antigen on the red blood cells (RBCs). It is named so because one of the eight Rh antigens (agglutinogen D) was originally identified in Rhesus monkeys. This antigen was originally discovered in Rhesus monkeys and later revealed in the humans. A person who is Rh+ contains Rh antigen, whereas the person who lacks the Rh antigen is known as Rh-.

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Imagine that you are a clinical geneticist. Your colleague is an oncologist who wants your help explaining the basics of genetics to their patient, who will be undergoing genetic testing in the coming weeks for possible acute myeloid leukemia (AML) induced by the radiation she had several years ago for breast cancer. Write a 1,050- to 1,225-word memo to your colleague. Include the following in your memo: An explanation of the molecular structure of DNA and RNA, highlighting both similarities and differences  A description of the processes of transcription and translation An explanation of the differences between leading and lagging strands and how the DNA is replicated in each strand Reponses to the following common questions patients might ask about this type of genetic testing and genetic disorder: Does AML run in families? What genes are tested for?
Respond to the following in a minimum of 175 words: What are some potential consequences that could result if the processes of replication, transcription, and translation don’t function correctly? Provide an example of how you might explain these consequences in terms that patients might understand.
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