Fundamentals of Anatomy & Physiology (10th Edition)
Fundamentals of Anatomy & Physiology (10th Edition)
10th Edition
ISBN: 9780321909077
Author: Frederic H. Martini, Judi L. Nath, Edwin F. Bartholomew
Publisher: PEARSON
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Chapter 10, Problem 1CC

How would a drug that inhibits AChE make a myasthenia gravis patient stronger?

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"One of the symmetry breaking events in mouse gastrulation requires the amplification of Nodal on the side of the embryo opposite to the Anterior Visceral Endoderm (AVE). Describe one way by which Nodal gets amplified in this region." My understanding of this is that there are a few ways nodal is amplified though I'm not sure if this is specifically occurs on the opposite side of the AVE.  1. pronodal cleaved by protease -> active nodal 2. Nodal -> BMP4 -> Wnt-> nodal 3. Nodal-> Nodal, Fox1 binding site  4. BMP4 on outside-> nodal  Are all of these occuring opposite to AVE?
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Fundamentals of Anatomy & Physiology (10th Edition)

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