Fundamentals of Biochemistry: Life at the Molecular Level
Fundamentals of Biochemistry: Life at the Molecular Level
5th Edition
ISBN: 9781118918401
Author: Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher: WILEY
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Chapter 10, Problem 19CQ

(a)

Summary Introduction

To explain: Whether miltefosine is a glycerophospholipid.

Concept introduction: The anti-parasitic drug miltefosine is considered as an alkylphosphocholine drug. It is demonstrated actively against various parasitic species and some pathogenic bacteria and fungi. This drug is mainly characterized for the long residence time in the body.

(b)

Summary Introduction

To explain: How does miltefosine cross the parasite cell membrane.

Concept introduction: The anti-parasitic drug miltefosine is considered as an alkylphosphocholine drug. It is demonstrated actively against various parasitic species and some pathogenic bacteria and fungi. This drug is mainly characterized for the long residence time in the body.

(c)

Summary Introduction

To explain: In what parts of the cell the drug mostly accumulates.

Concept introduction: The anti-parasitic drug miltefosine is considered as an alkylphosphocholine drug. It is demonstrated actively against various parasitic species and some pathogenic bacteria and fungi. This drug is mainly characterized for the long residence time in the body.

(d)

Summary Introduction

To explain: The feature common to all these compounds given is recognized by the protein.

Concept introduction: The anti-parasitic drug miltefosine is considered as an alkylphosphocholine drug. It is demonstrated actively against various parasitic species and some pathogenic bacteria and fungi. This drug is mainly characterized for the long residence time in the body.

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