Campbell Essential Biology with Physiology (6th Edition)
6th Edition
ISBN: 9780134711751
Author: Eric J. Simon, Jean L. Dickey, Jane B. Reece
Publisher: PEARSON
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Textbook Question
Chapter 10, Problem 11SQ
HIV requires an enzyme called _____ to convert its RNA genome to a DNA version. Why is this enzyme a particularly good target for anti-AIDS drugs? (Hint: Would you expect such a drug to harm the human host?)
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a. What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent.
b. What will happen to elimination of the drug in the previous question if the system is saturated? explain and show any math involved
If you wanted to reduce the difference between peak and trough levels that occur with repeated administration of a drug, how would you adjust the dose and dose interval without changing the plateau concentration (plateau is the average of peak and trough levels)? Select your answers for both dose and interval. Hint: It may be helpful to think about this problem using an example such as food. How would you eat if you wanted to maintain very steady hunger/satiety levels without changing your total caloric intake?
Options:
A. Dose; Increase dose
B. Dose; Decrease dose
C. Dose; Do not change dose
D. Interval; Increase the interval between doses (give the drug less frequently)
E. Interval; Decrease the interval between doses (give the drug more frequently)
F. Interval; Do not change the interval
What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent. Show the math
Chapter 10 Solutions
Campbell Essential Biology with Physiology (6th Edition)
Ch. 10 - A molecule of DNA contains two polymer strands...Ch. 10 - Name the three parts of every nucleotide.Ch. 10 - Prob. 3SQCh. 10 - A scientist inserts a radioactively labeled DNA...Ch. 10 - The nucleotide sequence of a DNA codon is GTA....Ch. 10 - Describe the process by which the information in a...Ch. 10 - Prob. 7SQCh. 10 - A geneticist finds that a particular mutation has...Ch. 10 - Scientists have discovered how to put together a...Ch. 10 - How do some viruses reproduce without ever having...
Ch. 10 - HIV requires an enzyme called _____ to convert its...Ch. 10 - Prob. 12IMTCh. 10 - Prob. 13IMTCh. 10 - Prob. 14IMTCh. 10 - A cell containing a single chromosome is placed in...Ch. 10 - In a classic 1952 experiment, biologists Alfred...Ch. 10 - Prob. 17PSCh. 10 - Prob. 18BSCh. 10 - Prob. 19BSCh. 10 - Flu vaccines have been shown to be safe, are very...
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