Chapter 1, Problem 3PP

I cannot understand why the ephedrine HCl is considered as a conjugated weak acid of the weak base ephedrine. I think I am missing out some concepts. I know the ibuprofen is a weak acid and ibuprofen sodium is a weak base I just memorised it cuz I cannot understand why. I only know sodium salt of wa acts a s wb. Sodium salt of wb acts as a weak acid

I am struggling with understand ing some concepts of pharmacology esp. how oxymetazoline use for nasal congestion, prazosin use for prostatic huperplasia and side effects. In addition I found I am struggling with explaining how to minimise the side effects of the inhaled corticosteroids.

1. Outline some potential causes of epilepsy (3 marks) 2. Explain the mechanism of action of the antiepileptic drug carbamazepine and mention one thing that patients should be aware of when taking it (4 marks) 3. What are neural tube defects and how do they relate to antiepileptic drugs? (3 marks) 4. What class does sertraline belong to and what is it’s mechanism of action? 5. Explain what “serotonin syndrome” is and how it is thought to occur at a pharmacological level? In your answer include at least TWO symptoms of this condition. (4 marks) 6. Lithium toxicity can result from high concentrations of lithium in the blood. What are the signs of lithium toxicity and what are TWO classes of drugs that might interact with lithium? (3 marks) 7. The following questions relate to antipsychotics a)Antagonist activity at which receptor is most likely to be responsible for causing drowsiness? (1 mark) b)Antipsychotics might also cause hyperprolactinemia. Antagonist activity at which…