Anatomy & Physiology
1st Edition
ISBN: 9781938168130
Author: Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark Womble
Publisher: OpenStax College
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Chapter 1, Problem 29CTQ
For whom would an appreciation of the structural characteristics of the human heart come more easily: an alien who lands on Earth, abducts a human, and dissects his heart, or an anatomy and physiology student performing a dissection of the heart on her very first day of class? Why?
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Biopharmaceutics and Pharmacokinetics:Two-Compartment Model Instant Absorption Questions
SHOW ALL WORK, including equation used, variables used and each step to your solution, report your regression lines and axes names (with units if appropriate) :Calculate a-q
a) B1,
b) B2,
c) hybrid rate constant (1)
d) hybrid rate constant (2)
e) t1/2,dist
f) t1/2,elim
g) k10
h) k12
i) k21
j) initial concentration (C0)
k) central compartment volume (V1)
l) steady-state volume (Vss)
m) clearance (CL) AUC (0→10 min) using trapezoidal rule
n) AUC (20→30 min) using trapezoidal rule
o) AUCtail (AUC360→∞)
p) total AUC (using short cut method)
q) volume from AUC (VAUC)
Glitazones reduce insulin resistance by binding to a transcription factor in adipocytes, thereby reducing thesecretion of fatty acids. Glitazones are taken orally (in pill form). Using pharmacokinetic modeling, deriveequations to describe how the concentration of glitazones varies in the plasma as a function of time. Yourequations should be of the form: dCglitazone /dt = something, or dMglitazone /dt = something. Your model shouldinclude three compartments: the gut, the plasma, and the fatty tissues. Make sure to include a diagram thatillustrates your thinking, state all assumptions, and define your variables. Do not solve the equations.
Chapter 1 Solutions
Anatomy & Physiology
Ch. 1 - View this animation...Ch. 1 - Water concentration in the body is critical for...Ch. 1 - A CT or CAT scan relies on a circling scanner that...Ch. 1 - A patient undergoing an MRI is surrounded by a...Ch. 1 - PET relies on radioactive substances administered...Ch. 1 - Which of the following specialties might focus on...Ch. 1 - A scientist wants to study how the body uses foods...Ch. 1 - The smallest independently functioning unit of an...Ch. 1 - A collection of similar tissues that performs a...Ch. 1 - The body system responsible for structural support...
Ch. 1 - Metabolism can be defined as the ________....Ch. 1 - Adenosine triphosphate (ATP) is an important...Ch. 1 - Cancer cells can be characterized as generic cells...Ch. 1 - Humans have the most urgent need for a continuous...Ch. 1 - Which of the following statements about nutrients...Ch. 1 - C.J. is stuck in her car during a bitterly cold...Ch. 1 - After you eat lunch, nerve cells in your stomach...Ch. 1 - Stimulation of the heat-loss center causes...Ch. 1 - Which of the following is an example of a normal...Ch. 1 - What is the position of the body when it is in the...Ch. 1 - To make a banana split, you halve a banana into...Ch. 1 - The lumbar region is ________. inferior to the...Ch. 1 - The heart is within the ________. cranial cavity...Ch. 1 - In 1901, Wilhelm Rontgen was the first person to...Ch. 1 - Which of the following imaging techniques would be...Ch. 1 - Which of the following imaging studies can be used...Ch. 1 - What are two major disadvantages of MRI scans?...Ch. 1 - Name at least three reasons to study anatomy and...Ch. 1 - For whom would an appreciation of the structural...Ch. 1 - Name the six levels of organization of the human...Ch. 1 - The female ovaries and the male testes are a part...Ch. 1 - Explain why the smell of smoke when you are...Ch. 1 - Identify three different ways that growth can...Ch. 1 - When you open a bottle of sparkling water, the...Ch. 1 - On his midsummer trek through the desert, Josh ran...Ch. 1 - Identify the four components of a negative...Ch. 1 - What regulatory processes would your body use if...Ch. 1 - In which direction would an MRI scanner move to...Ch. 1 - If a bullet were to penetrate a lung, which three...Ch. 1 - Which medical imaging technique is most dangerous...Ch. 1 - Explain why ultrasound imaging is the technique of...
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