You are trying to determine the optical purity (% enantiomeric excess) of a compound tha you have just synthesized. You measure the rotation of plane-polarized light of a 0.5 g/ml solution and find the rotation to be +16.2 degrees (clockwise). Given the pure (-) isomer has a specific rotation of -45 degrees, what is the optical purity of the compound? Show you work.
You are trying to determine the optical purity (% enantiomeric excess) of a compound tha you have just synthesized. You measure the rotation of plane-polarized light of a 0.5 g/ml solution and find the rotation to be +16.2 degrees (clockwise). Given the pure (-) isomer has a specific rotation of -45 degrees, what is the optical purity of the compound? Show you work.
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Transcribed Image Text:**Objective: Determine Optical Purity**
You are tasked with determining the optical purity (% enantiomeric excess) of a compound you have synthesized. A 0.5 g/mL solution is prepared, and the rotation of plane-polarized light is measured to be +16.2 degrees (clockwise). The pure (-) isomer of this compound has a specific rotation of -45 degrees. Calculate the optical purity of the compound, and show your work.
**Explanation of Terms:**
- **Optical Purity (% Enantiomeric Excess):** A measure of the excess of one enantiomer over the other in a mixture. It is calculated using the observed rotation and the specific rotation of the pure enantiomer.
- **Specific Rotation:** The rotation observed for a compound at a specified temperature and concentration.
- **Enantiomers:** Molecules that are mirror images of each other.
The task involves using the provided data to calculate the percentage of the predominant enantiomer in the mixture.
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