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Xeljanz is a medication used to treat rheumatoid arthritis. Draw the enantiomer of the molecule shown below. Use a dash or wedge bond to indicate stereochemistry of substituents on asymmetric centers, where applicable. N= N. N N 'N ZI

Xeljanz is a medication used to treat rheumatoid arthritis. Draw the enantiomer of the molecule shown below. Use a dash or wedge bond to indicate stereochemistry of substituents on asymmetric centers, where applicable. N= N. N N 'N ZI

Chemistry
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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**Transcription and Explanation** --- **Text:** "Xeljanz is a medication used to treat rheumatoid arthritis. Draw the enantiomer of the molecule shown below. Use a dash or wedge bond to indicate stereochemistry of substituents on asymmetric centers, where applicable." **Diagram:** The image presents a chemical structure of Xeljanz. It consists of multiple rings and heteroatoms, including nitrogen and oxygen. There is also a single stereocenter marked with a wedge bond to indicate its orientation. **Molecular Structure Overview:** 1. **Central Ring System:** - A six-membered piperidine ring is present with nitrogen as one of the atoms. - The nitrogen in the ring is connected to a methyl group. 2. **Attached Groups:** - There is an amide linkage with a double-bonded oxygen and a nitrogen atom extending from the piperidine ring. - The azole ring is fused to another benzene ring, forming a larger bicyclic system. **Workspace:** To the right side of the molecular diagram, there is a grid (honeycomb pattern) for drawing chemical structures. Below the grid, there is a selection of tools for adding atoms, bonds, and charges to the drawing: - Single, double, and triple bonds - Various stereochemical indicators like wedge bonds for depicting chiral centers - An assortment of functional groups and rings that can be added to the diagram This setup allows for the manipulation and construction of molecular models to understand chemical structures better. **Note for Educational Website:** This section is intended to help students or researchers explore and understand the stereochemistry of pharmaceutical compounds like Xeljanz. The tools provided in the diagram support learning and application of organic chemistry principles, particularly those involving chiral molecules and their enantiomers.
Transcribed Image Text:**Transcription and Explanation** --- **Text:** "Xeljanz is a medication used to treat rheumatoid arthritis. Draw the enantiomer of the molecule shown below. Use a dash or wedge bond to indicate stereochemistry of substituents on asymmetric centers, where applicable." **Diagram:** The image presents a chemical structure of Xeljanz. It consists of multiple rings and heteroatoms, including nitrogen and oxygen. There is also a single stereocenter marked with a wedge bond to indicate its orientation. **Molecular Structure Overview:** 1. **Central Ring System:** - A six-membered piperidine ring is present with nitrogen as one of the atoms. - The nitrogen in the ring is connected to a methyl group. 2. **Attached Groups:** - There is an amide linkage with a double-bonded oxygen and a nitrogen atom extending from the piperidine ring. - The azole ring is fused to another benzene ring, forming a larger bicyclic system. **Workspace:** To the right side of the molecular diagram, there is a grid (honeycomb pattern) for drawing chemical structures. Below the grid, there is a selection of tools for adding atoms, bonds, and charges to the drawing: - Single, double, and triple bonds - Various stereochemical indicators like wedge bonds for depicting chiral centers - An assortment of functional groups and rings that can be added to the diagram This setup allows for the manipulation and construction of molecular models to understand chemical structures better. **Note for Educational Website:** This section is intended to help students or researchers explore and understand the stereochemistry of pharmaceutical compounds like Xeljanz. The tools provided in the diagram support learning and application of organic chemistry principles, particularly those involving chiral molecules and their enantiomers.
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