Why is it important to proceed with the acetanilide formation before the nitration? The nitration is meta directed in aniline The nitration is deactivated in aniline. The nitration is directed towards the para position in acetanilide than in aniline The nitration is faster in acetanilide than in aniline

Q: The compound below is treated with N-bromosuccinimide (NBS) in the presence of light. Draw both…

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Q: This is Wittig Rxn:  Whatever mechanism you choose to draw is fine since you can leave the base as…

A: Wittig reaction is carried out between aldehyde or ketone and ylide to form the alkene .

Q: detailed mechanism of action of bisphenol A

A: Other chemicals including bisphenol S (BPS) and bisphenol F (BPF) have been evaluated as an…

Q: Carbodiimides are excellent coupling agents to use to allow an amide or ester coupling to occur…

A: The reagent DIC also called carbodiimide is a coupling agent for ester or amide formation. The…

Q: Which cannot be prepared in high yield treatment of a ketone or a diketone with a slight excess of…

A: LDA abstracts proton from the alpha position to the carbonyl group of ketone. The negative charged…

Q: Propose an efficient synthesis for each of the following

A: Alkenes on reaction with dilute sulphuric acid produce alcohol and on further oxidation produce the…

Q: Predict the major product of the following E2 reaction. CI A. B. C. D. JIII... f Strong, unhindered…

A: E2 elimination refers to a type of elimination reaction in organic chemistry. It stands for…

Q: Part 2 out of 2 Devise a synthesis of the biaryl whereby the methyl substituted ring is used to…

A: We have to synthesize the given biaryl compound. Concept: Suzuki coupling and aromatic reactions.

Q: nitration reaction Cmono-di or trisubstitubed benzene ring) - cannot he acetanilıde

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Q: CI, AICI3

A: This is an example of Friedel–Crafts alkylation. Friedel–Crafts alkylation generally gives…

Q: What type of product would form when LDA( strong base/weak nucleophile) is reacted with( methyl…

A: There is no reaction between methyl halide and LDA.

Q: Which of the starting materials could be used to prepare the below compound by an aldol reaction O…

A: Aldol condesation is the condenation reaction between the aldehyde or ketone compounds. The aldehyde…

Q: Identify the stronger nucleophile in the following pair of anions. Br− or Cl− in a polar protic…

A: A nucleophile is a species that contains a lone pair of electrons and has a negative charge on it.…

Q: 1. The diazonium salt is too reactive to store very long and is generated as needed. What product…

A: Diazonium salts are compounds containing the functional group −N2+, formed by the reaction of…

Q: Draw the two intermediates, including resonance structures, for the attack of nitronium ion on…

A: The substitution reactions of aromatic rings in which an atom in the ring is replaced by the…

Q: After the formation of the enolate anion, the intramolecular nucleophilic addition takes place.

A: Answer shown in attachment provide in explanation box Explanation:

Q: Now that we have synthesized the required aldehyde, the synthesis of ketone A can be accomplished,…

A: Given: Reaction.  To find : Suitable Reagents.  Solution: At first the Alkene attacks on carbonyl…

Q: he cyano group is often considered to be more stable than esters or even amides vhen reacting with a…

A: Introduction :  We have to tell why cyanide is a stable nucleophile.

Q: bJ HCl, traue peroxides

A: Which of these is the best reagent to affect the transformation? (a) HCl (b) HCl, peroxides (c)…

Q: Explain the E2 mechanism (bimolecular elimination) of of Elimination ?

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Q: All of the following are limitations to the Friedel - Crafts alkylation reaction except Highly…

A: The objective of the question is to identify the statement that is not a limitation of the…

Q: Choose the selective reagent that will form the intended product. ? Br 1. PPh3 2. BuLi (CH3)3CONa,…

A: In the given reaction the secondary alkyl bromide reacts with the sterically hindered strong base to…

Q: Select the di-carbonyl compound that would efficiently form the structure shown via an…

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Q: H. A

A: Propanal is an organic molecule which contains an aldehyde functional group. Total 3 molecules of…

Q: Draw the orthonitrophenolate product which absorbs light at 420nm.

A: ONPG is cleaved and forms ONP that is ortho nitrophenol which is yellow in colour and absorbs light…

Q: Predict the major products formed when the following reacts with a mixture of concentrated HNO3 and…

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Reactions at the Alpha Carbon Atom

The position next to the ketone or aldehyde functional group is termed as alpha position and the reaction which occurs at alpha position is called alpha substitution reaction. In an alpha substitution reaction, the alpha proton atom is substituted by an electrophile by the formation of an enol intermediate or enolate ion intermediate. Most of the carbonyl compounds go through an alpha substitution reaction.