Why have HIV protease inhibitors such as retinovir have been formulated into soft gelatin capsules?
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Why have HIV protease inhibitors such as retinovir have been formulated into soft gelatin capsules?
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- Do the plasmids integrate into the host genome when the AAV is introduced into the patient? Explain.Tat and Rev proteins are required for HIV replication. What are their roles and why are they essential to the virus?15) Why are viruses an ideal candidate for gene delivery in gene therapy? a) What are TWO limitations of viruses as gene delivery vectors in gene therapy?
- At which stage of viral infection did these mutations most likely occur? a.) Attachment b.) Entry c.) Uncoating d.) Protein syntheis e.) Genome replicaton f.) Assembly g.) ExitWhich of the following proteins would you expect a mutation in for a virus to infect a new host cell? RNA Dependent RNA polymerase/Reverse Transcriptase/DNA polymerase/etc. Hemagglutinin/Glycoprotein/GP120/etc. Fusion protein Capsid/Nucleocapsid proteins Why? What is that protein responsible for?Please answer the following statement with yes or false. If your answer is incorrect it will delete the correct answer 43)..The end products for the RNA dependent RNA polymerase is ssRNA. 44) ...The end products of the DNA dependent RNA polymerase is ss RNA. 45)..The end products of the viral RNA dependent DNA polymerase is SSDNA ..The end product of the viral DNA dependent DNA polymerase is SSDNA 46). 47) .The end product of the viral integrase enzyme is a provirus. 48) The end product of the PB1 enzyme is SSDNA
- The genome of which of the following types of animal virus can act directly as MRNA and be utilized by ribosomes without prior processing? O 1) retroviruses O 2) SSDNA viruses 3) -SSRNA viruses O 4) +SSRNA viruses 5) dsDNA virusesThe same molecular process that causes antigenic drift in HIV can lead to resistance to some antiretroviral drugs used in HIV therapy. Which of the following explains why a combinationdifferent antiretroviral drugs is more effective than a single antiretroviral drug? Select ALL that apply.a).Each antiretroviral drug has a different mechanism of action and targets a different aspect of HIV replication.b).By using 3 different antiretroviral drugs at the same time, it is highly unlikely that a combination of mutations conferring drug resistance will occur at the same time.c)Administering 3 antiretroviral drugs achieves higher levels of each drug than administering just one antiretroviral drug.d).By using 3 different antiretroviral drugs, these drugs are likely to be more effective in inhibiting the same HIV enzyme than one antiretroviral drug.e),Administering 3 antiretroviral drugs is less toxic than administering one antiretroviral drug.