Why carbon C-2 and C-5 are mark? why not just ona carbon is marked since just one carbon was marked on pyruvate?
Why carbon C-2 and C-5 are mark? why not just ona carbon is marked since just one carbon was marked on pyruvate?
Gluconeogenesis is the synthesis of glucose molecules from non-carbohydrate sources such as pyruvate, lactate, glycerol, propionate, and glucogenic amino acids. During the synthesis of glucose molecules from pyruvate, initially the pyruvate molecules in the cytosol are transported into the mitochondria and converted into oxaloacetate. Inside the mitochondria, oxaloacetate is converted into malate, and this malate is transported to the cytosol. In the cytosol, the malate is converted into oxaloacetate and oxaloacetate is converted into phosphoenolpyruvate. Starting from phosphoenolpyruvate, rest of the reactions of gluconeogenesis are just opposite of the glycolytic pathway.
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