Which two amino acids are shown on the left side of Figure 3? Use Figure 2 to answer this. To which chemical groups do these amino acids belong? Were you able to identify their chemical characteristics based on your rules? If not, you should go back and revise your rules!

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
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**Exercise B: Peptide Bond Formation**

Figure 3 shows two individual amino acids, and then those same two amino acids after they have been linked together by a **peptide bond** to form a **dipeptide**. Addition of more amino acids linked by peptide bonds would form a **polypeptide**, the precursor to a functional protein.

[Diagram of two amino acids combining into a dipeptide through a peptide bond. The structures show amino groups, carboxyl groups, and R groups, highlighting the bond formation.]

*Figure 3. Formation of a peptide bond between two amino acids.*

**Answer the below questions in your own document.**

- Which two amino acids are shown on the left side of Figure 3? Use Figure 2 to answer this.
- To which chemical groups do these amino acids belong?
- Were you able to identify their chemical characteristics based on your rules? If not, you should go back and revise your rules!

On the dipeptide shown in Figure 3, label the **peptide bond** that was formed when the two individual amino acids were joined. Label the free **amino and carboxyl groups** at the ends of this dipeptide (not in the R groups). These are often referred to as the **N-terminus** (amino-terminus) and the **C-terminus** (carboxyl-terminus) of a peptide or polypeptide. (Note: “peptide” refers to a chain of a small number of amino acids, whereas “polypeptide” refers to a longer chain, potentially that corresponding to an entire protein.)
Transcribed Image Text:**Exercise B: Peptide Bond Formation** Figure 3 shows two individual amino acids, and then those same two amino acids after they have been linked together by a **peptide bond** to form a **dipeptide**. Addition of more amino acids linked by peptide bonds would form a **polypeptide**, the precursor to a functional protein. [Diagram of two amino acids combining into a dipeptide through a peptide bond. The structures show amino groups, carboxyl groups, and R groups, highlighting the bond formation.] *Figure 3. Formation of a peptide bond between two amino acids.* **Answer the below questions in your own document.** - Which two amino acids are shown on the left side of Figure 3? Use Figure 2 to answer this. - To which chemical groups do these amino acids belong? - Were you able to identify their chemical characteristics based on your rules? If not, you should go back and revise your rules! On the dipeptide shown in Figure 3, label the **peptide bond** that was formed when the two individual amino acids were joined. Label the free **amino and carboxyl groups** at the ends of this dipeptide (not in the R groups). These are often referred to as the **N-terminus** (amino-terminus) and the **C-terminus** (carboxyl-terminus) of a peptide or polypeptide. (Note: “peptide” refers to a chain of a small number of amino acids, whereas “polypeptide” refers to a longer chain, potentially that corresponding to an entire protein.)
The image provides a detailed chart showing the structures of the 20 natural amino acids, categorized by their chemical properties.

### Categories and Structures:

1. **Nonpolar Amino Acids:**
   - **Glycine:** H\(_2\)N-CH\(_2\)-COO\(^-\)
   - **Alanine:** H\(_2\)N-CH(CH\(_3\))-COO\(^-\)
   - **Valine:** H\(_2\)N-CH(CH(CH\(_3\))\(_2\))-COO\(^-\)
   - **Leucine:** H\(_2\)N-CH(CH\(_2\)-CH(CH\(_3\))\(_2\))-COO\(^-\)
   - **Methionine:** H\(_2\)N-CH(CH\(_2\)-S-CH\(_3\))-COO\(^-\)
   - **Isoleucine:** H\(_2\)N-CH(CH(CH\(_3\))-CH\(_2\)-CH\(_3\))-COO\(^-\)
   - **Phenylalanine:** H\(_2\)N-CH(CH\(_2\)-C\(_6\)H\(_5\))-COO\(^-\)
   - **Tyrosine:** H\(_2\)N-CH(CH\(_2\)-C\(_6\)H\(_4\)-OH)-COO\(^-\)
   - **Tryptophan:** H\(_2\)N-CH(CH\(_2\)-C\(_8\)H\(_6\)N)-COO\(^-\)
   - **Proline:** H\(_2\)N-CH\(_2\)-CH\(_2\)-CH\(_2\)-CH\(_2\)-COO\(^-\)

2. **Polar (Uncharged) Amino Acids:**
   - **Serine:** H\(_2\)N-CH(CH\(_2\)-OH)-COO\(^-\)
   - **Threonine:** H\(_2\)N-CH(CH(OH)-CH\(_3\))-COO\(^-\)
   - **Cysteine:** H\(_2
Transcribed Image Text:The image provides a detailed chart showing the structures of the 20 natural amino acids, categorized by their chemical properties. ### Categories and Structures: 1. **Nonpolar Amino Acids:** - **Glycine:** H\(_2\)N-CH\(_2\)-COO\(^-\) - **Alanine:** H\(_2\)N-CH(CH\(_3\))-COO\(^-\) - **Valine:** H\(_2\)N-CH(CH(CH\(_3\))\(_2\))-COO\(^-\) - **Leucine:** H\(_2\)N-CH(CH\(_2\)-CH(CH\(_3\))\(_2\))-COO\(^-\) - **Methionine:** H\(_2\)N-CH(CH\(_2\)-S-CH\(_3\))-COO\(^-\) - **Isoleucine:** H\(_2\)N-CH(CH(CH\(_3\))-CH\(_2\)-CH\(_3\))-COO\(^-\) - **Phenylalanine:** H\(_2\)N-CH(CH\(_2\)-C\(_6\)H\(_5\))-COO\(^-\) - **Tyrosine:** H\(_2\)N-CH(CH\(_2\)-C\(_6\)H\(_4\)-OH)-COO\(^-\) - **Tryptophan:** H\(_2\)N-CH(CH\(_2\)-C\(_8\)H\(_6\)N)-COO\(^-\) - **Proline:** H\(_2\)N-CH\(_2\)-CH\(_2\)-CH\(_2\)-CH\(_2\)-COO\(^-\) 2. **Polar (Uncharged) Amino Acids:** - **Serine:** H\(_2\)N-CH(CH\(_2\)-OH)-COO\(^-\) - **Threonine:** H\(_2\)N-CH(CH(OH)-CH\(_3\))-COO\(^-\) - **Cysteine:** H\(_2
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