Which reaction or reactions of glycolysis require NAD* as a reactant? Which reaction or reactions in glycolysis require NADH as a reactant?

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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### Glycolysis and the Role of NAD⁺ and NADH

**Question:**

Which reaction or reactions in glycolysis require NAD⁺ as a reactant?

**Explanation:**

In glycolysis, NAD⁺ is required during the conversion of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate, which is catalyzed by the enzyme glyceraldehyde-3-phosphate dehydrogenase. This reaction involves the reduction of NAD⁺ to NADH.

**Question:**

Which reaction or reactions in glycolysis require NADH as a reactant?

**Explanation:**

Glycolysis itself does not consume NADH as a reactant; however, NADH is produced and later used in cellular respiration to generate ATP, primarily through oxidative phosphorylation. In some anaerobic conditions, NADH is reoxidized to NAD⁺ through processes like fermentation.
Transcribed Image Text:### Glycolysis and the Role of NAD⁺ and NADH **Question:** Which reaction or reactions in glycolysis require NAD⁺ as a reactant? **Explanation:** In glycolysis, NAD⁺ is required during the conversion of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate, which is catalyzed by the enzyme glyceraldehyde-3-phosphate dehydrogenase. This reaction involves the reduction of NAD⁺ to NADH. **Question:** Which reaction or reactions in glycolysis require NADH as a reactant? **Explanation:** Glycolysis itself does not consume NADH as a reactant; however, NADH is produced and later used in cellular respiration to generate ATP, primarily through oxidative phosphorylation. In some anaerobic conditions, NADH is reoxidized to NAD⁺ through processes like fermentation.
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