Which one of the following amino acids is phosphorylated during the process of promoter clearance by eukaryotic RNA polymerase II? threonine Otyrosine serine proline

Biochemistry
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ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
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Chapter1: Biochemistry: An Evolving Science
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Which one of the following amino acids is phosphorylated during the process of
promoter clearance by eukaryotic RNA polymerase II?
Othreonine
tyrosine
serine
Oproline
Transcribed Image Text:Which one of the following amino acids is phosphorylated during the process of promoter clearance by eukaryotic RNA polymerase II? Othreonine tyrosine serine Oproline
Expert Solution
Step 1

In eukaryotes RNA Polymerase II is responsible for the synthesis of mRNA.

The largest subunit of Pol II has C-terminal domain called the CTD that is the target of kinases and phosphatases.

The phosphorylation of the CTD is important in mechanisms related to transcriptional regulation.

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