Which of the following substituents is the strongest activating group in electrophilic aromatic substitution reactions with benzene? A) -CH(CH:): B) -SO:H C) -CI D) -OH E) -CO:CH3

Q: Explain the reactivity and orientation effects observed in each heterocycle.a. Pyridine is less…

A: Aromatic compounds generally shows electrophilic substitution reactions. In electrophilic…

Q: draw mechanism for the reaction B. N 1) NBS 2) KNO3 Conc. H₂SO4

A: NBS is bromination reagent. It undergoes bromination according to electrophilic aromatic…

Q: Arrange the given compounds in the increasing order of reaction rate for EAS (Electrophilic Aromatic…

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Q: Which is the major isolated organic product of this reaction sequence? (A) Br Br 1. NaOCH3 2. Br₂…

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Q: Rank the following alkyl halides in order of increasing SyI reactivity. Br Br B: Br C: А: A B C…

A: In SN1 reaction formation of carbonation takes place so the reactivity of that alkyl or Aryl halide…

Q: Circle which of the following ions will be good leaving groups in sn1 and sn2 reactions?

A: Leaving group is the one that accepts a lone pair when the bond between it and its neighbouring…

Q: Usually at the 2- or 3- position, Thiophene undergoes electrophilic aromatic substitution. Draw the…

A: Organic reactions are those in which organic reactant react to form organic products. In the above…

Q: Draw a stepwise mechanism for the following transformation: Part 1: Part 2 out of 3 OH view…

A: An equilibrium lies between keto form (-C=O) and enol form (-C= C-OH) called Keto-enol Tautomerism.

Q: Example #1: b a Example #2: a b Predict the substitution pattern when this compound undergoes a…

A: "Since you have posted multiple questions,we will provide the solution only for first question as…

Q: 7. Which substituent would be classified as a deactivating ortho/para director in an electrophilic…

A: In electrophilic aromatic substitution:Electron donating groups (EDG) are activating and ortho/para…

Q: ArCN 1) LIAIH/EtO 2) H" (aq) hv b) 2 Benzophenone + Isopropyl Alcohol 1) NaBHExOH Hexanal 2) H"(aq)…

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Q: 11. Rank the following in order of reactivity in electrophilic aromatic substitution A CF3 A LEAST…

A: AActivating groups are substituents that increase the rate of a reaction Example  CH3; c2H5…

Q: Part 4: Reactions: Complete the following reactions by providing the correct product(s), starting…

A: 17. Hydroboration–oxidation reaction: Alkene gives an electrophilic addition reaction with borane.…

Q: 1. Identify the nucleophile and electrophile in each reaction below and label them. €0. a) b) :O:…

A: Organic reagents can be divided into two categories electrophile and nucleophile on the basis of the…

Q: Which of the following would be LEAST reactive for electrophilic aromatic substitution? a) CH b) Oc…

A: This answer is given below.Explanation:

Q: 1. LDA, -78 °C 2. PhCH₂Br (1 equiv) ☑ ☑ OH Select to Draw Please select a drawing or reagent from…

A: The LDA, -78oC will form a kinetic enolate. Then the enolate attacks on PhCh2Br in order to form a…

Q: CH3 H3C

A: As we know, electron withdrawing groups decreases the ring towards electrophilic aromatic…

Q: What specific electrophile is attacked by benzene when it undergoes nitration?

A: Electrophile means electron-loving species or we can say the species which is deficient in electrons…

Q: Indicate whether each structure is aromatic, nonaromatic, or antiaromatic. Treat all structures as…

A: Aromaticity refers to the special stability and unique chemical properties exhibited by certain…

Q: A CrO 3 H2SO4 но но

A: The given product is a carboxylic acid and the reagent is (CrO3 + H2SO4 + H2O). This reagent is…

Q: 3) Provide the structure of the major organic product in the following reaction. CH3 4) Classify the…

A: Step 1: Step 2: Step 3: Step 4:

Q: 9. Rank the compounds below in order of reactivity to Electrophilic Aromatic Substitution. Rank the…

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Q: Which compound(s) A B are anti-aromatic? Assume planarity. NH C N= D NH E

A: The structures of the given molecules are  Identify the molecules are which are anti-aromatic:

Q: 3Jab = 10 Hz На Hb 3Jbc = 7 Hz CI CI Hc Hc

A: Jab = 10Hz Jbc=7Hz Ha will split Hb into doublet of 10Hz separation, Later Hc will cause that…

Q: None

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Q: Provide a plausible arrow pushing mechanism for the reaction below. 1 eq. H20 + МеОн HO, OMe cat.…

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Q: H 1. LDA 2. CH31 H J = J -H CH₂ Monocarbonyl compounds can be alkylated at the a position via the…

A: Answer:  Mechanism is shown in the explanation area.Explanation:Step 1:

Q: Identify the aromatic compound which cannot undergo the Friedel-Crafts reaction with CH3Cl/AlCl3.

A: Compound (C) cannot undergo the Friedel-Crafts reaction with CH3Cl/AlCl3.  Reason : Due to…

Reactions of Ethers

Ethers (R-O-R’) are compounds formed by replacing hydrogen atoms of an alcohol (R-OH compound) or a phenol (C6H5OH) by an aryl/ acyl group (functional group after removing single hydrogen from an aromatic ring). In this section, reaction, preparation and behavior of ethers are discussed in the context of organic chemistry.

Epoxides

Epoxides are a special class of cyclic ethers which are an important functional group in organic chemistry and generate reactive centers due to their unusual high reactivity. Due to their high reactivity, epoxides are considered to be toxic and mutagenic.

Williamson Ether Synthesis

An organic reaction in which an organohalide and a deprotonated alcohol forms ether is known as Williamson ether synthesis. Alexander Williamson developed the Williamson ether synthesis in 1850. The formation of ether in this synthesis is an SN2 reaction.