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- What does rhe binding of ACh to nicotinic receptors of skeletal muscle cells directly cause? Closing of calcium channels Cross bridge cycling Hydrolysis of ATP Inhibition of acetylcholinesterase Skeletal muscle depolarizationSelect the True regarding neurotransmitter mechanism : It acts peripherally at neuromuscular junction (NMJ) to increase skeletal muscle contraction as follow: O Nicotinic receptor antagonist O Nicotinic receptor agonist O M2 receptor antagonist O GABA A receptors agonistsReferring to the figure below, which letter (s) indicate (s) the site (s) of action of methylxanthines? O a. A+B O b. Only B O c. Only C O d. Only A O e. Only D Acetylcholine D Bronchodilation Bronchial tone Bronchoconstriction CAMP ACO C PDE Adenosina ATP AMP Mest Coll Medidas al klaalery Processes
- Riluzole (Rilutek) may extend the life expectancy of ALS patients by: Promoting Acetylcholine release Interfering with glutaminergic neurotransmission Increases the size & efficiency of skeletal muscle cells None of the aboveHow does botox decrease muscle tone? inhibits acetylcholinesterase prevents the release of ACh opens SR calcium channels damages lower motor neurons recruits more motor unitsWhich of the following structures has activity like acetylcholine? Et H3C Me H3C NMeg H.C NMes
- Why is salbutamol better than isoproterenol in asthma management in terms of agonistic effect?What is the target for the following compound? O Muscarinic receptor O Acetylcholinesterase enzyme O Choline acetyltransferase O Nicotinic receptor O None of the answers MezN OEt fo QEtA _______________ is a drug that causes temporary paralysis by blocking the transmis- sion of nerve stimuli to the muscles. neuromuscular blocker skeletal muscle relaxant
- Students in a veterinary school are given the following hypotheticalproblem: A dog ingests organophosphate poison, and the students areresponsible for saving the animal’s life. Organophosphate poisons bindto and inhibit acetylcholinesterase. Several substances the studentscould inject include the following: acetylcholine, curare (which blocksacetylcholine receptors), and potassium chloride. If you were a studentin the class, what would you advise to save the animal?Which of the following would result in higher force production at lower action potential frequencies W. increase SERCA activity X. increase DHPR sensitivity Y. increase acetylcholineesterase activity Z. increase Ca2+ releaseWhat does the binding of ACh to nicotinic receptors of skeletal muscle cells directly cause? Closing of calcium channels Cross-bridge cycling O Hydrolysis of ATP O Inhibition of acetylcholinesterase O Skeletal muscle depolarization