Which of the following statements about homeobox (hox) genes is FALSE?

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Which of the following statements about homeobox (hox) genes is FALSE?
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They direct the development of an overall body plan
They DO vary greatly from species to species and are NOT “highly conserved”
Subtle differences in hox gene action are responsible for physical differences in closely related species.
They DO NOT vary greatly from species to species and ARE “highly conserved”
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